Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 16 , ISSUE S1 ( April, 2024 ) > List of Articles


Malignant Struma Ovarii—Management and Follow-up of a Rare Ovarian Tumor: A Case Report

Shikha S Thakur, Shaheen Anjum, Shagufta Qadri

Keywords : Case report, Dermoid cyst, Mature cystic teratoma, Patient care technician, Struma ovarii

Citation Information :

DOI: 10.5005/jp-journals-10006-2385

License: CC BY-NC 4.0

Published Online: 06-03-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Mature cystic ovarian teratomas (MCT) are the commonest germ cell tumors accounting for about 30–45% of all ovarian neoplasms and 60% of all benign neoplasms arising in the ovary. Only 2% of MCTs undergo malignant transformation. We report a rare case of a 48-year-old woman diagnosed with a primary malignant struma ovarii arising in a dermoid cyst of the ovary. The patient was admitted with the complaint of pelvic pain and a pelvic mass in the lower abdomen on gynecological examination and ultrasonography showed a dermoid cyst of the ovary. Preoperative tumor markers and routine biochemistry were unremarkable. A laparoscopic left-sided salpingo-oophorectomy was done. Histopathology of the tissue showed a malignant struma ovarii and immunohistochemistry (CK-19 levels) similar to the guidelines for primary thyroid gland disease. The patient was subsequently taken up for staging laparotomy with total abdominal hysterectomy with right salpingo-oophorectomy and retroperitoneal pelvic and para-aortic lymphadenectomy and omentectomy. The histopathological report of all staging tissues was normal and surgical staging IA was assigned. Thyroglobulin level was monitored in the postoperative period. She is free of the disease for the last 2 years.

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