Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 16 , ISSUE S1 ( April, 2024 ) > List of Articles

CASE SERIES

Pelvic Organ Prolapse in Young Balinese Women: A Case Series

Kadek F Marta, Olivia L Prawoto, Made BD Aryana, Ryan S Mulyana

Keywords : Ligament, Pelvic, Prolapse, Treatment

Citation Information :

DOI: 10.5005/jp-journals-10006-2384

License: CC BY-NC 4.0

Published Online: 06-03-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Introduction: Pelvic organ prolapse (POP) is an important health problem but it is still receiving little attention, patients often seek medical help only when the disease is very disturbing/severe. Case description: This case report describes a series of three cases of POP in young women who had similar profiles in terms of several characteristics, including age, occupation, ethnicity, BMI, parity, age of the youngest child (years), number of vaginal deliveries, operative vaginal deliveries, episiotomy, birth weight of the largest child, family history of prolapse, diagnosis, and procedures performed. In this case series, conservative operative treatment (Purandare hysteropexy) was carried out, then an examination of the sacrouterine ligament tissue was performed from the operation. The results of the examination showed a decrease in the expression of type I collagen, an increase in type III collagen, an increase in the levels of matrix metalloproteinases-2 (MMP-2), and MMP-9 which based on previous studies are found in patients with POP. Conclusion: Conservative treatment with Purandare hysteropexy was done in all cases, further research is needed to establish whether this condition is the cause of the occurrence of POP in young people and the genetic correlation associated with the disorder.


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