Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 16 , ISSUE 2 ( March-April, 2024 ) > List of Articles

Original Article

Endometrial Histology in Epithelial Ovarian Tumors: A Critical Analysis

Priya Dharshini

Keywords : Bioactive E2, SF-1, Stromal steroidogenesis

Citation Information : Dharshini P. Endometrial Histology in Epithelial Ovarian Tumors: A Critical Analysis. J South Asian Feder Obs Gynae 2024; 16 (2):65-67.

DOI: 10.5005/jp-journals-10006-1913

License: CC BY-NC 4.0

Published Online: 23-02-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Objective: The aim of the present study is to determine the prevalence of abnormal endometrial histology, premalignancy, and malignancy in women diagnosed with epithelial ovarian tumors and tumor-like conditions (PCOS, endometriosis, stromal hyperplasia, and stromal hyperthecosis). Materials and methods: Endometrial and ovarian specimens of 71 patients with epithelial ovarian tumors were retrospectively selected, and the histopathology was analyzed. Moreover, 79% had serous tumors, 15.4% had mucinous tumors, and 5.6% other tumors (fibrothecoma, cystadenofibroma). Ovarian histopathology was compared with the concurrent endometrial pathology. Results: Among the samples analyzed, 41% had abnormal endometrial histology, of which 29% is polypoidal endometrium and 12% is disordered proliferation, both of which represent hyperestrogenic state. Conclusion: Abnormal endometrial histology due to stromal steroidogenesis and its biological action on endometrium is well-known; hence, endometrial evaluation is mandatory for planning treatment and understanding the disease process of epithelial ovarian tumors.

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