VOLUME 15 , ISSUE 6 ( November-December, 2023 ) > List of Articles
Amitha Vijay Kamat, Sucheta Suresh
Keywords : Mean arterial pressure, Oral hydration therapy, Preterm preeclampsia, Prolongation of pregnancy
Citation Information : Kamat AV, Suresh S. A Clinical Trial of Oral Hydration Therapy for the Management of Very Preterm Nonsevere Preeclampsia. J South Asian Feder Obs Gynae 2023; 15 (6):679-682.
DOI: 10.5005/jp-journals-10006-2354
License: CC BY-NC 4.0
Published Online: 04-12-2023
Copyright Statement: Copyright © 2023; The Author(s).
Background and objectives: To compare the effectiveness of oral hydration therapy compared with controls in decreasing mean arterial pressure and extending the duration of pregnancy in very preterm preeclampsia. Materials and methods: Forty-five cases of preterm preeclampsia between 20 and 34 weeks of gestation who were admitted to the Department of Obstetrics and Gynaecology, KIMS, Hubballi, were included in the study. They were randomized into two groups and intervened with oral hydration therapy and a control group, which was not on any intervention. Both groups were given adequate antihypertensives for control of BP. Outcome measures were a fall in BP, prolongation of pregnancy, and improved maternal and neonatal outcomes. Results: It was observed that diastolic BP significantly reduced in oral hydration group after 5 days of starting treatment (p = 0.020). The average weight of babies in oral hydration therapy group was 2.5 kg (p = 0.011) and 2 kg in controls. Mean prolongation of pregnancy among oral hydration group was 38.6 days (p = 0.037) and 26.7 days (p = 0.249) in controls. Conclusion: Oral hydration therapy was more useful to improve fetal outcome compared with maternal outcome. It was useful to prolong pregnancy and to increase fetal birth weight. It was not found as useful for improving maternal outcome or in decreasing mean arterial pressure. Though most of the outcomes were better in oral hydration therapy clinically, it was not statistically significant. Hence, larger studies maybe required to prove their difference in outcome.