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VOLUME 15 , ISSUE 5 ( September-October, 2023 ) > List of Articles

Original Article

Assessment of Abnormal Uterine Bleeding and Histological Relations Using Hysteroscopy-guided Biopsy: An Observational Study Over a Decade in a Tertiary Care Center

Vineet V Mishra, Smit B Solanki, Athulya Shajan

Keywords : Abnormal uterine bleeding, Biopsy, Hysteroscopy

Citation Information : Mishra VV, Solanki SB, Shajan A. Assessment of Abnormal Uterine Bleeding and Histological Relations Using Hysteroscopy-guided Biopsy: An Observational Study Over a Decade in a Tertiary Care Center. J South Asian Feder Obs Gynae 2023; 15 (5):505-508.

DOI: 10.5005/jp-journals-10006-2316

License: CC BY-NC 4.0

Published Online: 31-10-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Objective: Assessing the findings of hysteroscopy and histologic diagnosis in women who have abnormal uterine bleeding (AUB). The scenario is a sequential retrospective series of patients in a tertiary care hospital. Patients: From January 2012 to December 2022, 1,090 individuals with AUB had hysteroscopies with biopsy. Methods: Hysteroscopies were performed using 2.9- or 4-mm telescopes, and the distension solution was glycine or saline. With a 5-mm grasper or resectoscope, biopsies were performed. Histologic evaluation of biopsies and prevalence of hysteroscopic findings are the primary outcome measures. Results: Normal uterine cavity and cervical canal were found in 759 (69.62%) patients. Submucous fibroids were diagnosed in 22 women. Endometrial polyps were discovered in 26 (2.38%) of the patients. Endometrial hyperplasia was detected in 166 (15.22%) of the women, while endometrial cancer was diagnosed in 4 of them (0.36%). Conclusion: The most common histologic diagnosis was normal endometrium.

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  1. Collins J, Crosignani PG; ESHRE Capri Workshop Group. Endometrial bleeding. Hum Reprod Update 2007;13(5):421–431. DOI: 10.1093/humupd/dmm001.
  2. Breijer M, Timemermans A, van Doorn HC, et al. Diagnostic strategies for postmenopausal bleeding. Obstet Gynecol Int 2010;2010:850812. DOI: 10.1155/2010/850812.
  3. Bradley H, Nezhat F. Hysteroscopy. In: Nezhat C, editor. Nezhat's Operative Gynecologic Laparoscopy and Hysteroscopy. New York: Cambridge University Press; 2008, pp. 577–579.
  4. Baggish M, Guedj H, Valle R. General aspects of operative hysteroscopy. In: Baggish M, Guedj H, Valle R, editors. Hysteroscopy: Visual Perspectives of Uterine Anatomy, Physiology and Pathology, 3rd edition. London: Lippincott Williams & Wilkins; 2007, pp. 330–359.
  5. van Dongen H, de Kroon CD, Jacobi CE, et al. Diagnostic hysteroscopy in abnormal uterine bleeding: A systematic review and meta-analysis. BJOG 2007;114(6):664–675. DOI: 10.1111/j.1471-0528.2007.01326.x.
  6. Nikolaou D, Salman G, Richardson R. Operative hysteroscopy in the outpatient in the outpatient setting: Its role within a gynaecology service. Gynaecol Surg 2009;6:21–24. DOI: 10.1007/s10397-008-0406-x.
  7. Singhi A. Comparison of complications rates in endoscopic surgery performed by a clinical assistant vs. An experienced endoscopic surgeon. J Gynecol Endosc Surg 2009;1(1):40–46. DOI: 10.4103/0974-1216.51909.
  8. Baggish M. Anatomy of the uterus. In: Baggish M, Guedj H, Valle R, editors. Hysteroscopy: Visual Perspectives of Uterine Anatomy, Physiology and Pathology, 3rd edition. London: Lippincott Williams & Wilkins; 2007, pp. 15–30.
  9. Lasmar RB, Dias R, Barrozo PR, et al. Prevalence of hysteroscopic findings and histologic diagnoses in patients with abnormal uterine bleeding. Fertil Steril 2008;89:1803–1807. DOI: 10.1016/j.fertnstert.2007.05.045.
  10. Sunitha CH. A Clinical Study of Diagnostic Hysteroscopy in Abnormal Uterine Bleeding and its Histopathological Correlation; Dissertation. Bijapur: Shri B.M. Patil Medical College Hospital and Research Centre; 2006, p. 236.
  11. Decloedt JF, Fenton DW. Outpatient hysteroscopy: Indications and hysteroscopic findings in pre-and postmenopausal patients. Gynaecol Endosc 1999;8:137–141. DOI: https://doi.org/10.1046/j.1365-2508.1999.00258.x
  12. de Jong P, Doel F, Falconer A. Outpatient diagnostic hysteroscopy. Br J Obstet Gynaecol 1990;97(4):299–303. DOI: 10.1111/j.1471-0528.1990.tb01805.x.
  13. Dibi RP, Zettler CG, Pessini SA, et al. Tamoxifen use and endometrial lesions: Hysteroscopic, histological, and immunohistochemical findings in postmenopausal women with breast cancer. Menopause 2009;16(2):293–300. DOI: 10.1097/gme.0b013e31818af10a.
  14. Cove H. Surgical Pathology of the Endometrium, 5th edition. Lippincott Williams & Wilkins; 1981, pp. 72–77.
  15. Fleihmann CF. Text Book of Menstrual Disorder and Treatment, 16th edition. Blackwell; 1956. pp. 306.
  16. William BJ, Roberston. The Abnormal Menstrual Cycle: Text Book of Endometrium, 4th edition. Butterworth; 1981. pp. 45–72.
  17. Brown R. Clinical fractures associated with endometrial carcinoma. J Obstet Gynaecol Br Commonw 1974;81:933–939. PMID: 4452920.
  18. Dallenbach–Hellwag G. Histopathology of the Endometrium. Berlin: Springer–Verlag; 1981. pp. 26–31.
  19. Eufinger H. Zir Frage den Menstruation S Mechanismus. Geburtshife Fraunenheilkd 1952;12:1014.
  20. Steive H. Angeblich Sterile Zeiten im Leben geschlechtsluchliger frauen. Z Geburtshilfe Gynakol 1952;136:117. PMID: 14951435.
  21. Schmidt–Mathieren H. Histochemische ontersuchungen der endometrium – Ground substans. Acla Histochem 1962;13:129–164. PMID: 13908819.
  22. Taubert HD. Luteal phase insufficiency. 1978;4:78–113. PMID: 679688.
  23. Fox H, Buckley CH. Pathological factors involved in infertility. In: Blausterin A, editor. Pathology of the Female Genital Tract. Springer Verlag; 1982. pp. 828–837.
  24. Ancla M, de Brux J, Musset R, et al. Electron microscope study of human endometrium in different conditions of hormonal equilibrium. Arch Anat Pathol 1967;15(Suppl.):136–145. PMID: 5599705.
  25. Thomas R, Reid RL. Thyroid disease and reproductive dysfunction: A review. Obstet Gynaecol 1987;70(5):789–798. PMID: 3309753.
  26. Mazzaferri EL. Evaluation and Management of common thyroid disorders in women. American J Obstet Gynecol 1997;176(3):507–514. DOI: 10.1016/s0002-9378(97)70538-6.
  27. Kistner RW. Gynecological Principles and Practice. Chicago: Year Book Publishers; 1964. p. 238.
  28. Novak ER, Jones JS, Jones HW. Novak's Textbook of Gynecology, 8th edition. Baltimore: Lippincott Williams & Wilkins; 1971. p. 319.
  29. Verma U, Garg R, Singh S, et al. Diagnostic approach in perimenopausal women with abnormal uterine bleeding. J South Asian Feder Menopause Soc 2014;2(1):12–14. DOI: 10.5005/jp-journals-10032-1025.
  30. Agarwal P, Garg R, Rai N, et al. Abnormal uterine bleeding. J South Asian Feder Menopause Soc 2016;4(1):22–26. DOI: 10.5005/jp-journals-10032-1080.
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