Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 14 , ISSUE 5 ( September-October, 2022 ) > List of Articles


Hypothyroidism masquerading as Ovarian Malignancy: A Case Report

L Kavin Nilavu, Manoranjan Mahapatra, Jita Parija

Keywords : Galactorrhea, Hypothyroidism, Ovarian cyst, Pituitary hyperplasia, Risk of malignancy index 1

Citation Information : Nilavu LK, Mahapatra M, Parija J. Hypothyroidism masquerading as Ovarian Malignancy: A Case Report. J South Asian Feder Obs Gynae 2022; 14 (5):614-615.

DOI: 10.5005/jp-journals-10006-2115

License: CC BY-NC 4.0

Published Online: 16-11-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Background: Ovarian cysts are the most common indication for surgery. Some cysts are due to endocrine dysfunction and mostly do not require surgery. Case description: We report a case of a 32-year-old female who presented with large ovarian masses and pituitary enlargement seen in association with hypothyroid. Initially, her radiological imaging and risk of malignancy index (RMI) were in favor of malignancy. On further workup of the patient, high thyroid stimulating hormone (TSH) and prolactin levels were found and she was planned for surgery after optimization. There was a dramatic symptomatic relief as well as a decrease in the size of the ovarian mass after four months of thyroxin supplementation. Conclusion: In young patients presenting with bilateral multicystic ovarian masses, a thyroid function test is mandatory and if thyroid dysfunction is detected, it should be addressed before any surgical intervention. Clinical significance: Hypothyroidism should be considered in differential diagnosis of female with multicystic ovarian mass.

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  1. Cai J, Zhang Y, Wang Y, et al. High thyroid stimulating hormone level is associated with hyperandrogenism in euthyroid polycystic ovary syndrome (PCOS) women, independent of age, BMI, and thyroid autoimmunity: A cross-sectional analysis. Front Endocrinol 2019;10:222. DOI: 10.3389/fendo.2019.00222.
  2. Ansari MS, Almalki MH. Primary hypothyroidism with markedly high prolactin. Front Endocrinol 2016;7:35. DOI: 10.3389/fendo.2016.00035.
  3. Tresa A, Rema P, Suchetha S, et al. Hypothyroidism presenting as ovarian cysts: A case series. Indian J Surg Oncol 2021;12(Suppl 2): 343–347. DOI: 10.1007/s13193-020-01263-8.
  4. Aziz K, Shahbaz A, Umair M, et al. Hyperprolactinemia with galactorrhea due to subclinical hypothyroidism: A case report and review of literature. Cureus 2018;10(5). DOI: 10.7759/cureus.2723.
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