Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 14 , ISSUE 5 ( September-October, 2022 ) > List of Articles

CASE REPORT

A Fatal Case of Ovarian Hyperstimulation Syndrome

Eshita Davinder Wadhwa, Archana Anilkumar Bhosale, Shweta Avinash Khade, Smurti Kamble, Snehal Shivaji Shinde, Arun Harishchandra Nayak

Keywords : Assisted reproductive technique, Gonadotropin releasing hormone antagonists and agonists, Ovarian hyperstimulation, Ovum donor

Citation Information : Wadhwa ED, Bhosale AA, Khade SA, Kamble S, Shinde SS, Nayak AH. A Fatal Case of Ovarian Hyperstimulation Syndrome. J South Asian Feder Obs Gynae 2022; 14 (5):611-613.

DOI: 10.5005/jp-journals-10006-2108

License: CC BY-NC 4.0

Published Online: 16-11-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim: This case report is aimed to study an ovum donor, hospitalized with severe ovarian hyperstimulation syndrome (OHSS) and anuria. Background: Ovarian hyperstimulation syndrome is an iatrogenic complication now on the rise with the increasing use of assisted reproductive technologies and ovulation induction. The syndrome can range from mild symptoms to life-threatening conditions. Case description: A 30-year-old patient with abdominal distention, anuria, and ultrasonography suggestive of grossly enlarged ovaries. The patient was managed with hemodialysis and multidisciplinary approach until she had an ovarian follicular rupture with hemoperitoneum and had to undergo surgical management. Conclusion: Patients with high risk for OHSS should be hospitalized and monitored closely when undergoing assisted reproductive methods like intrauterine insemination or ovulation induction. The condition is managed by medical therapy and surgical intervention is required only if the ovarian cysts rupture, undergoes torsion or patient starts debilitating vitally. Clinical significance: Careful selection of candidates for assisted reproductive technology (ART), close monitoring and prompt management can control the progression of OHSS from mild to critical and can be lifesaving.


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  1. Tomás C, Colmorn L, Rasmussen S, et al. Annual incidence of severe ovarian hyperstimulation syndrome. Dan Med J 2021;68(2):A12190738. PMID: 33543701.
  2. Alper MM, Smith LP, Sills ES. Ovarian hyperstimulation syndrome: current views on pathophysiology, risk factors, prevention, and management. J Exp Clin Assist Reprod 2009;6:3. PMID: 20485578.
  3. Le Gouez A, Naudin B, Grynberg M, et al. Le syndrome d'hyperstimulation ovarienne [Ovarian hyperstimulation syndrome]. Ann Fr Anesth Reanim 2011;30(4):353–362. DOI:10.1016/j.annfar.2010.11.026.
  4. Yadav P, Singh S, Singh R, et al. To study the effect on fertility outcome by gonadotropins vs laparoscopic ovarian drilling in clomipheneresistant cases of polycystic ovarian syndrome. J South Asian Feder Obst Gynae 2017;9(4):336–340.
  5. Garg R, Singh S, Jain M. Cabergoline for ovarian hyperstimulation: a review of clinical evidence. J South Asian Feder Obst Gynae 2015;7(1):30–32. DOI:10.5005/jp-journals-10006-1317.
  6. Shaw W, Shaw W, Padubidri V, et al. Shaw's textbook of Gynaecology. London 2015;552–553.
  7. Lodh M, Mukhopadhyay J, Sharma V. A case of severe ovarian hyperstimulation syndrome. Indian J Clin Biochem 2014;29(3):386–389. DOI:10.1007/s12291-013-0390-4.
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