Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 14 , ISSUE 4 ( July-August, 2022 ) > List of Articles


Cellular Angiofibroma of the Vulva: A Rare Case Report

Amit Basu, Rajni Bansal, Upasna Sharma, Srabani Auddy Basu

Keywords : Cellular angiofibroma, Histopathology, Immunohistochemistry, Mesenchymal tumors, Vulva

Citation Information : Basu A, Bansal R, Sharma U, Basu SA. Cellular Angiofibroma of the Vulva: A Rare Case Report. J South Asian Feder Obs Gynae 2022; 14 (4):473-474.

DOI: 10.5005/jp-journals-10006-2090

License: CC BY-NC 4.0

Published Online: 22-08-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Aim: To describe clinical, histological, and immunohistochemical features of cellular angiofibroma, a rare mesenchymal tumor of vulva. Background: Cellular angiofibroma are rare mesenchymal tumors. These tumors have two principal components spindle cells and hyalinized stroma with small to medium sized vessels. Cellular angiofibroma (CAF) are benign in nature. Cellular angiofibroma commonly occurs after fifth decade. Characterization requires histological and immunohistochemical evaluation. Case description: We report a case of 65-year-old postmenopausal woman presenting with a painless and gradually enlarging mass in the clitoral region of vulva near external urethral meatus. A simple excision of the mass was performed. Gross examination of the mass showed a well circumscribed lesion of 5.5 cm × 5.5 cm. Histological and immunohistochemical analysis established a diagnosis of cellular angiofibroma. The tumor can recur, but distant metastasis of the tumor has not yet been described in the literature. Conclusion: Cellular angiofibroma is a rare benign tumor of vulva for which simple excision is adequate treatment. Differentiation of this tumor from other sarcomatous lesions can be done with histological and immunological evaluation.

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