Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 14 , ISSUE 4 ( July-August, 2022 ) > List of Articles


Vaginal Leiomyosarcoma: Fundamental Dilemma Prevails

Vinita Singh, Pragati Trigunait, Purnima Singh, Taru Shikha, Pushpawati Thakur, Chandrashekhar Shrivastava

Keywords : Adjuvant radiotherapy, Chemotherapy, Immunohistochemistry, Vaginal leiomyosarcoma

Citation Information : Singh V, Trigunait P, Singh P, Shikha T, Thakur P, Shrivastava C. Vaginal Leiomyosarcoma: Fundamental Dilemma Prevails. J South Asian Feder Obs Gynae 2022; 14 (4):465-467.

DOI: 10.5005/jp-journals-10006-2085

License: CC BY-NC 4.0

Published Online: 22-08-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Smooth muscle tumors, though rare, are reported to be the most common benign and malignant mesenchymal tumors in adult women. Leiomyosarcomas may originate from any part of the vagina and are mostly submucosal. Patients usually present with vaginal discharge or bleeding or rarely dyspareunia and micturition. Vaginal leiomyosarcoma is a very aggressive tumor with fast local invasion and metastasis to distant organs. Radical resection by surgery remains the best treatment, and we continue to recommend surgical resection as the primary treatment. The role of adjuvant radiotherapy and chemotherapy is not clearly defined and can be considered optional in high-grade sarcomas to prevent recurrence, invasion, or spreading of the tumor. However, usually, it does not improve the survival of the patient.

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