COVID-19 pandemic, COVID-19 and pregnancy, Pregnancy, Pregnancy outcome
Citation Information :
Goyal R, Saxena P, Mittal M, Chaudhary G, Grover MS. Clinical Profile of COVID-19 Positive Obstetric Patients Admitted to a Tertiary Care Hospital during the Two Waves of COVID-19. J South Asian Feder Obs Gynae 2022; 14 (4):440-444.
Background: Coronavirus disease 2019 (COVID-19), a global pandemic which undoubtedly hit the whole world so hard. There have been multiple waves across the globe of varying time, duration, and intensity, India has also witnessed two waves sweeping the entire nation. The second wave had startling intensity with massively increased oxygen requirement, intensive care unit (ICU) admissions. The effect was even more pronounced in the pregnant women as there was increased maternal morbidity and mortality. However, there are limited reports on the impact of COVID-19 during pregnancy.
Objective: This study is aimed at highlighting the variance in clinical profile of pregnant patients in first and second wave of COVID-19 in India.
Materials and methods: A retrospective observational comparative hospital-based study was conducted in a tertiary care hospital in Delhi during the two waves of COVID-19. The first wave in India lasted from May 2020 to October 2020, and the second wave lasted from April 2021 to June 2021.We obtained the medical records and compiled clinical and outcome data for all pregnant patients, who were admitted in the Department of Obstetrics and Gynaecology of our Hospital during the first and second wave of pandemic with a laboratory-confirmed report of SARS-CoV-2.
Results and conclusion: The second wave definitely saw more number of symptomatic patients, an increase in symptom of shortness of breath, increase in oxygen requirement, ICU admissions, marginally increase lower segment cesarean section (LSCS) rates and associated comorbidity such as hypertensive disease of pregnancy.
Andrews MA, Areekal B, Rajesh KR, et al. First confirmed case of COVID-19 infection in India: a case report. Indian J Med Res 2020;151(5):490–492. DOI: 10.4103/ijmr.IJMR_2131_20.
Worldometer. COVID-19 coronavirus pandemic. 2021; published online, 19 October 2021. Available at: https://www.worldometers.info/coronavirus/country/india/ Accessed: 19 October 2021.
Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China of novel coronavirus-infected pneumonia. N Engl J Med 2020;382(13):1199–1207. DOI: 10.1056/NEJMoa2001316.
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395(10223):497–506. DOI: 10.1016/S0140-6736(20)30183-5.
Agarwal N, Garg R, Singh S, et al. A corona virus disease 2019 in pregnancy: maternal and perinatal outcome. J Edu health Promot 2021;10:194. DOI: 10.4103/jehp.jehp_954_20.
Nambiar SS, S Ajith, VP Reshmi. Assessing disease outcome in COVID-19 pregnancies in a tertiary referral center in South India: a single-center retrospective cohort study. J South Asian Feder Obst Gynae 2020;12(5):335–339. DOI: 10.5005/jp-journals-10006-1822.
Kapadia SN, Mehta A, Mehta CR, et al. Study of pregnancy with COVID-19 and its clinical outcomes in a tertiary care teaching hospital in Western India. J South Asian Feder Obst Gynae 2021;13(2):125–130. DOI: 10.5005/jp-journals-10006-1886.
Jamieson DJ, Theiler RN, Rasmussen SA. Emerging infections and pregnancy. Emerg Infect Dis. 2006;12(11):1638–1643. DOI: 10.3201/eid1211.060152.
Favre G, Pomar L, Musso D, et al. 2019-nCoV epidemic: what about pregnancies? Lancet 2020;395(10224):e405. DOI: 10.1016/S0140-6736(20)30311-1.
Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses 2020;12(2):194. DOI: 10.3390/v12020194.
Zhao J, Yang Y, Huang H. Relationship between the ABO blood group and the COVID-19 susceptibility. Clin Infect Dis 2021;73(2):328–331. DOI: 10.1093/cid/ciaa1150.
Sorci G, Faivre B, Morand S. Explaining among-country variation in COVID-19 case fatality rate. Sci Rep 2020;10(1): 18909. DOI: 10.1038/s41598-020-75848-2.
Dashraath P, Wong JLJ, Lim MXK. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol 2020;222(6):521–531. DOI: 10.1016/j.ajog.2020.03.021.
Kadiwar S, Smith JJ, Ledot S, et al. Were pregnant women more affected by COVID-19 in the second wave of the pandemic? Lancet 2021;397(10284):1539–1540. DOI: 10.1016/S0140-6736(21)00716-9.
Malhotra J, Garg R. Corona virus disease (COVID-19) and pregnancy: what obstetrician should know? JSAFOG 11(6):337–339. DOI: 10.5005/jp-journals-10006-1744.
Malhotra N, Garg R, Singh S. Pregnancy management in coronavirus disease: challenges in developing countries. J Reprod Healthc Med 2021;2:18. DOI: 10.25259/JRHM_58_2020.
Malhotra N, Malhotra N, Garg R. COVID and women's health in India. J Indian Med Assoc 2022;120(3):xx.
Volz E, Mishra S, Chand M. Transmission of SARS-CoV-2 lineage B.1.1.7 in England: insights from linking epidemiological and genetic data. medRxiv 2021 DOI: 10.1101/2020.12.30.20249034.