Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 14 , ISSUE 2 ( March-April, 2022 ) > List of Articles


Endometrial Stromal Nodule: A Rarity and Diagnostic Challenge

R Karthikeyan, Kaarthiga R Gopinath

Keywords : Endometrial stromal nodule, Endometrial stromal tumors, Low-grade endometrial stromal sarcoma

Citation Information : Karthikeyan R, Gopinath KR. Endometrial Stromal Nodule: A Rarity and Diagnostic Challenge. J South Asian Feder Obs Gynae 2022; 14 (2):205-206.

DOI: 10.5005/jp-journals-10006-2034

License: CC BY-NC 4.0

Published Online: 21-06-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Background: Endometrial stromal tumors (ESTs) are rare tumors arising from the uterus. The incidence of EST is 2 per million women. Endometrial stromal nodules (ESNs) are rare subtype of ESTs and they are benign tumors. We describe a case of ESN since it is a rare tumor and the clinical presentation was different. Case description: A 54-year-old perimenopausal woman, para 2, live 2 presented with complaints of lower abdomen pain for 2 months. Clinical features, ultrasound, and contrast-enhanced computed tomography (CECT) abdomen report were suggestive of malignant ovarian tumor. Tumor markers were within normal limits. Staging laparotomy was done. Solid mass of 9 × 6 × 6 cm arising from uterine fundus above which large cystic lesion measuring 21 × 18 × 13 cm was seen. Both side fallopian tubes and ovaries were normal. The morphological, microscopic, and immunohistochemical features of that solid with cystic mass were consistent with ESN. Preoperatively suspected malignant ovarian tumor case later turned out to be ESN. Conclusion: There is no definitive test available to confirm ESN before surgery. Usually, it is diagnosed postoperatively and the clinical presentation could be variable like in our case. Clinical significance: High-grade endometrial stromal sarcoma (HGESS) can be differentiated from low-grade endometrial stromal sarcoma (LGESS) by gross appearance, microscopic features, mitotic state, and immunohistochemistry.

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