Journal of South Asian Federation of Obstetrics and Gynaecology

Register      Login

VOLUME 14 , ISSUE 2 ( March-April, 2022 ) > List of Articles

Original Article

An Observational Study to Assess the Role of Modified Biophysical Profile and Doppler Ultrasound in Determining the Fetal Well-being in Low-risk Term Pregnancy

H Sonia, HU Bhavya, Geeta Doppa

Keywords : Amniotic fluid index, Antepartum fetal surveillance, Low-risk pregnancy, Modified biophysical profile, Non-stress test, Term pregnancy, Ultrasound Doppler

Citation Information : Sonia H, Bhavya H, Doppa G. An Observational Study to Assess the Role of Modified Biophysical Profile and Doppler Ultrasound in Determining the Fetal Well-being in Low-risk Term Pregnancy. J South Asian Feder Obs Gynae 2022; 14 (2):144-147.

DOI: 10.5005/jp-journals-10006-2054

License: CC BY-NC 4.0

Published Online: 21-06-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aims and objectives: To determine the tests of antepartum fetal surveillance such as Doppler ultrasound, modified biophysical profile (MBP) alone, and in combination for assessing adverse neonatal outcome in term low-risk pregnancy. Materials and methods: Prospective observational study was done in a rural tertiary care center for 1 year duration. A total of 169 term low-risk pregnant women were included in the study and fetal surveillance tests such as MBP and Doppler ultrasound were done. The sensitivity of MBP and Doppler analysis in predicting the neonatal outcome using parameters such as birth asphyxia, meconium-stained amniotic fluid (MSAF), neonatal intensive care unit (NICU) admission, and Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) score were assessed. Results: Among 169 pregnant women, MBP was normal in 66% and abnormal in 34% cases. 150 (89%) showed normal Doppler indices and 19 (11%) were found abnormal. Those with normal MBP and with normal Doppler were found to have better neonatal outcome and this was statistically meaningful (p <0.00). Doppler sensitivity was 37.5% and MBP was 62.5%. The results of combination of MBP and Doppler showed higher sensitivity of 73.5%. Conclusion: Modified biophysical profile was found to be a more significant than Doppler analysis in determining fetal well-being and in presage of fetal distress. Together MBP and Doppler analysis has yielded a higher sensitivity to detect adverse neonatal outcome. Clinical significance: Even if Doppler ultrasound is unavailable for surveillance, MBP alone can be the best modality to determine reassuring status in low-risk pregnancy.


PDF Share
  1. Finberg HJ, Kurtz AB, Johnson RL, et al. The biophysical profile: a literature review and reassessment of its usefulness in the evaluation of fetal well-being. J Ultrasound Med 1990;9(10):583–591. DOI: 10.7863/jum.1990.9.10.583.
  2. Manning FA, Platt LD, Sipos L. Antepartum fetal evaluation: Development of a fetal biophysical profile. American J Obstet Gynecol 1980;136(6):787–795. DOI: 10.1016/0002-9378(80)90457-3.
  3. Nageotte MP, Towers CV, Asrat T, et al. Perinatal outcome with the modified biophysical profile. Am J Obstet Gynecol 1994;170(6): 1672–1676. PMID: 8203424.
  4. Alfirevic Z, Stampalija T, Gyte GM. Fetal and umbilical Doppler ultrasound in normal pregnancy. Cochrane Database Syst Rev 2010;4(8):CD001450. DOI: 10.1002/14651858.CD001450.pub3.
  5. Rutherford SE, Phelan JP, Smith CV, et al. The four-quadrant assessment of amniotic fluid volume: an adjunct to antepartum fetal heart rate testing. ObstetGynecol 1987;70(3 Pt 1):353–356. PMID: 3306497.
  6. Ertan AK, Hendrik HJ, Tanriverdi HA, et al. Fetomaternal Doppler sonography nomograms. Clin Exp Obstet Gynecol 2003;30(4): 211–216. PMID: 14664415.
  7. Bardakci M, Balci O, Acar A, et al. Comparison of modified biophysical profile and Doppler ultrasound in predicting the perinatal outcome at or over 36 weeks of gestation. Gynecol Obstet Invest 2010;69(4): 245–250. DOI: 10.1159/000274488.
  8. Bakay K, Varolan A, Yazgan A, et al. Comparison of modified biophysical profile with Doppler ultrasonographic analysis in determining fetal well being in the third trimester. Gynecol Obstet Reprod Med [Internet]. 2013 [cited 2022 January10];19(2):67–75. Available from: https://gorm.com.tr/index.php/GORM/article/view/189.
  9. Borade J, Sharma S. The role of modified biophysical profile in predicting perinatal outcome in high-risk pregnancies. Int J Reprod Contracept Obstet and Gynecol 2018;7(6):2287–2294. http://dx.doi.org/10.18203/2320-1770.ijrcog20182337.
  10. Talukdar R, Deka N, Rahman M. Clinical study regarding the significance of Doppler and modified biophysical profile in the management of post-dated pregnancy. Sch Int J Obstet Gynec 2019;02(11):277–283. DOI: 10.36348/sijog.2019.v02i11.005.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.