Aim: The aim of the article was to enumerate the outcomes observed in fetuses with ductus venosus agenesis (DVA) in a tertiary care center.
Methodology: A retrospective observational study was conducted at the fetal medicine unit of a tertiary care center between July 2015 and July 2020. Outcomes were followed up for all fetuses diagnosed with DVA.
Results: A total of 14 patients were diagnosed with DVA in this study period. One patient was lost to follow-up and outcomes of 13 fetuses were studied. Nine patients presented with isolated DVA. Four patients had associated anomalies and underwent termination of pregnancy. Of the remaining nine fetuses with isolated DVA, eight survived with good neonatal outcomes.
Conclusion: Among eight fetuses with DVA without hepatic bypass (89%) and one fetus with intrahepatic umbilical venous drainage (IHD) (11%), seven of eight fetuses (88%) with isolated DVA had good neonatal outcomes. One fetus with intrahepatic drainage also had a good outcome. This leads to the impression that with close monitoring of the fetuses with DVA, particularly those without hepatic bypass, a good neonatal outcome can be expected.
Clinical significance: DVA is a rare anomaly. It is known to be associated with chromosomal abnormalities, structural defects, fetal growth restriction (FGR), and intrauterine fetal demise. Evaluation of ductus venosus (DV) at 11–13+6 weeks scan increases the diagnosis of DVA and its associated anomalies. This helps in the early detection of cardiac anomalies in these fetuses, and additionally, they benefit from close monitoring with serial Doppler evaluation.
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