Citation Information :
Karmakar S, Bid S, Maiti TK. Effects of Induction of Labor on Maternal and Perinatal Outcome in Postdated Nulliparous Pregnancy. J South Asian Feder Obs Gynae 2021; 13 (2):106-110.
Objective: This study aimed at determining the mode of delivery, maternal, and perinatal outcomes of induction of labor (IOL) in postdated pregnancies.
Methods: It was a prospective observational study. Nulliparous women with uncomplicated singleton pregnancies who have crossed their estimated date of delivery (EDD) were included in the study. Inclusion and exclusion criteria were strictly followed. A total of 280 patients were divided into study and control groups. Those who underwent IOL immediately after EDD were compared with women who were managed expectantly up to 42 weeks.
Results: The study group and control group consisted of 150 and 130 women, respectively. The rate of cesarean section (CS) (64.62%) was significantly higher in an expectantly managed group. The most common indication of the CS was fetal distress in both groups, and the occurrence of oligohydramnios was quite higher in the control group. The rate of shoulder dystocia, cervical tear, and third- and fourth-degree perineal tear was significantly more in an expectantly managed group. Fetal distress was also more in that group.
Conclusion: Our study suggests that labor should be induced after crossing EDD if gestational age is confirmed so that the incidence of maternal and perinatal complications can be brought down to an acceptable level.
ACOG (American College of Obstetricians and Gynecologists). Management of postterm pregnancy. ACOG Practice bulletin no. 55. Obstet Gynecol 2004;104:639–646. DOI: 10.1097/00006250-200409000-00052.
Crowley P. Interventions for preventing or improving the outcome of delivery at or beyond term (Cochrane review). In: The Cochrane library. Chicester: John Wiley & Sons, Ltd., 2004.
Olesen AW, Basso O, Olsen J. An estimate of the tendency to repeat postterm delivery. Epidemiology 1999;10:468–469. DOI: 10.1097/00001648-199907000-00026.
Divon MY, Ferber A, Nisell H, et al. Male gender predisposes to prolongation of pregnancy. Am J Obstet Gynecol 2002;187:1081–1083. DOI: 10.1067/mob.2002.126645.
Stotland NE, Washington AE, Caughey AB. Pre-pregnancy body mass index and length of gestation at term. Am J Obstet Gynecol 2007;197:378.e1. DOI: 10.1016/j.ajog.2007.05.048.
Laursen M, Bille C, Olesen AW, et al. Genetic influence on prolonged gestation: a population-based Danish twin study. Am J Obstet Gynecol 2004;190:489–494. DOI: 10.1016/j.ajog.2003.08.036.
Hilder L, Costeloe K, Thilaganathan B. Prolonged pregnancy: evaluating gestation-specific risks of fetal and infant mortality. Br J Obstet Gynaecol 1998;105:169–173. DOI: 10.1111/j.1471-0528.1998.tb10047.x.
Hannah ME. Postterm pregnancy: should all women have labour induced? A review of the literature. Fetal Matern Med Rev 1993;5:3. DOI: https://doi.org/10.1017/S0965539500000681
Alexander JM, McIntire DD, Leveno KJ. Prolonged pregnancy: induction of labour and caesarean births. Obstet Gynecol 2001;97:911. DOI: 10.1016/s0029-7844(01)01354-0.
Boulvain M, Stan C, Irion O. Membrane sweeping for induction of labour. Cochrane Database Syst Rev 2005;1:CD000451. DOI: 10.1002/14651858.CD000451.pub3.
Schaffir J. Survey of folk beliefs about induction of labor. Birth 2002;29:47–51. DOI: 10.1046/j.1523-536x.2002.00047.x.
Kavanagh J, Kelly AJ, Thomas J. Breast stimulation for cervical ripening and induction of labour. Cochrane Database Syst Rev 2005;3:CD003392. DOI: 10.1002/14651858.CD003392.pub2.
Smith CA, Crowther CA. Acupuncture for induction of labour. Cochrane Database Syst Rev 2004;1:CD002962. DOI: 10.1002/14651858.CD002962.pub2.
Rozenberg P, Chevret S, Ville Y. Comparison of pre-induction ultrasonographic cervical length and Bishop score in predicting risk of caesarean section after labour induction with prostaglandins. Gynecol Obstet Fertil 2005;33:17–22. DOI: 10.1016/j.gyobfe.2004.11.006.
Torricelli M, Novembri R, Voltolini C, et al. Biochemical and biophysical predictors of the response to the induction of labour in nulliparous postterm pregnancy. Am J Obstet Gynecol 2011;204:39.e1. DOI: 10.1016/j.ajog.2010.08.014.
Grobman WA, Rice MM, Reddy UM, et al. Labour induction versus expectant management in low risk nulliparous women. NEJM 2018;379(6):513–523. DOI: 10.1056/NEJMoa1800566.
Stock SJ, Ferguson E, Duffy A, et al. Outcomes of elective induction of labour compared with expectant management: population-based study. BMJ 2012;344:e2838. DOI: 10.1136/bmj.e2838.
Wolfe H, Timofeev J, Tefera E, et al. Risk of caesarean in obese nulliparous women with unfavourable cervix: elective induction vs expectant management at term. Am J Obstet Gynecol 2014;211:530. DOI: 10.1016/j.ajog.2014.01.034.
Vrouenraets FP, Roumen FJ, Dehing CJ, et al. Bishop score and risk of caesarean delivery after induction of labour in nulliparous women. Obstet Gynecol 2005;105:690–697. DOI: 10.1097/01.AOG.0000152338.76759.38.
Prysak M. Elective induction versus spontaneous labour: a case-control analysis of safety and efficacy. Obstet Gynecol 1998;92:47–52. DOI: 10.1016/s0029-7844(98)00115-x.
WHO. WHO recommendation for induction of labour. Geneva: World Health Organisation, 2011.
Oz AU, Holub B, Mendilcioglu I, et al. Renal artery doppler investigation of the etiology of oligohydramnios in postterm pregnancy. Obstet Gynecol 2002;100:715. DOI: 10.1016/s0029-7844(02)02203-2.
Trimmer KJ, Leveno KJ, Peters MT, et al. Observation on the cause of oligohydramnios in prolonged pregnancy. Am J Obstet Gynecol 1990;163:1900. DOI: 10.1016/0002-9378(90)90771-x.
Treger M, Hallak M, Silberstein T, et al. Post-term pregnancy: should induction of labour be considered before 42 weeks? J Matern Fetal Neonatal Med 2002;11:50–53. DOI: 10.1080/jmf.220.127.116.11.
Rand L, Robinson JN, Economy KE, et al. Postterm induction of labour revited. Obstet Gynecol 2000;96:779–783. DOI: 10.1016/s0029-7844(00)01002-4.
Hutcheon JA, Harper S, Strumpf EC, et al. Using interinstitutional practice variation to understand the risk and benefits of routine labour induction at 41(+0) weeks. BJOG 2015;122:973–981. DOI: 10.1111/1471-0528.13007.
Bonder-Adler B, Bodner K, Pateisky N, et al. Influence of labour induction on obstetric outcomes in patients with prolonged pregnancy. Wien Klin Wchenschr 2005;117:287–292. DOI: 10.1007/s00508-005-0330-2.
Bruckner TA, Cheng YW, Coughey AB. Increased neonatal mortality among normal weight births beyond 41 weeks of gestation in California. Am J Obster Gynecol 2008;199:4210–4219. DOI: 10.1016/j.ajog.2008.05.015.
Olesen AW, Westergaard JG, Olsen J. Perinatal and maternal complications related to postterm delivery: a national register-based study, 1978–1993. Am J Obstet Gynecol 2003;189:222–227. DOI: 10.1067/mob.2003.446.
Liu A, Lv J, Hu Y, et al. Efficacy and safety of intravaginal misoprostol versus intracervical dinoprostone for labour induction at term: a systemic review and meta-analysis. J Obstet Gynecol Res 2014;40(4):897–906. DOI: 10.1111/jog.12333.
Indira Mani Y, Ratnakumari V, Chaitanya Sravanthi TS. Induction of labour with vaginal misoprostol and incidence of meconium stained liquor and fetal outcome. JEBMH 2016;3(7):221–225.
Christensen FC, Tehranifar M, Gonzalez JL, et al. Randomized trial of concurrent oxytocin with a sustained-release dinoprostone vaginal insert for labour induction at term. Am J Obstet Gynecol 2002;186(1):61–65. DOI: 10.1067/mob.2002.118309.
Thangarajah F, Scheufen P, Kirn V, et al. Induction of labour in late and postterm pregnancies and its impact of maternal and neonatal outcome. Geburtshilfe Frauenheilkd. 2016;76(7):793–798. DOI: 10.1055/s-0042-107672.
Alexander JM, McIntire DD, Leveno KJ. Forty weeks and beyond: pregnancy outcomes by weeks of gestation. Obstet Gynecol 2000;96:291–294. DOI: 10.1016/s0029-7844(00)00862-0.
Wang M, Fontaine P. Common questions about late-term and postterm pregnancy. Am Fam Physician 2014;90:160–165.
Mandruzzato G, Alfirevic Z, Chervenak F, et al. Guidelines for management of postterm pregnancy. J Perinat Med 2010;38:111–119. DOI: 10.1515/jpm.2010.057.
Nakling J, Becke B. Pregnancy risk increases from 41 weeks of gestation. Acta Obstet Gynecol Scand 2006;85:663–668. DOI: 10.1080/00016340500543733.