Leiomyomas are benign smooth muscle tumors of the uterus found in 20 to 50% of women of reproductive age. The objective of this study was to evaluate the fetomaternal outcome in women having pregnancy with uterine leiomyomas. We compared the clinical, obstetric data, perinatal outcomes of 28 patients from a retrospective study of 5 years in our hospital. Twenty-eight pregnant women with fibroid >5 cm were included in our study. Major proportion of patients with fibroids were in younger age group of 20 to 25 and 25 to 30 years when compared with older age group of 31 to 35 years. Fibroids were more frequent in primigravida compared with multigravida. The complications were acute abdomen, cephalopelvic disproportion, antepartum hemorrhage (APH), preterm labor, malpresentation, postpartum hemorrhage (PPH), dysfunctional labor, intrauterine growth restriction (IUGR), and retained products of placenta. Cesarean section was done in 100% of women who attained term pregnancy and one patient had technical difficulty during cesarean section with intramural fibroid extending to lower segment of size 15 × 11 cm. Because of these complications, the pregnancy with fibroids should be considered as high-risk pregnancy.