Journal of South Asian Federation of Obstetrics and Gynaecology

Register      Login

VOLUME 9 , ISSUE 4 ( October-December, 2017 ) > List of Articles

RESEARCH ARTICLE

Study on the Prevalence and Characteristics of Metabolic Syndrome in Women of Reproductive Age Group with Polycystic Ovarian Syndrome

Rekha R Madusudhanan, Bindu Nambisan, Mayadevi Brahmanandan, Sreekumari Radha

Citation Information : Madusudhanan RR, Nambisan B, Brahmanandan M, Radha S. Study on the Prevalence and Characteristics of Metabolic Syndrome in Women of Reproductive Age Group with Polycystic Ovarian Syndrome. J South Asian Feder Obs Gynae 2017; 9 (4):341-347.

DOI: 10.5005/jp-journals-10006-1526

License: CC BY 3.0

Published Online: 01-07-2016

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

Introduction

Polycystic ovarian syndrome (PCOS) is an endocrine disorder affecting all age groups and presenting with myriad problems like menstrual irregularities, hirsutism, anovulatory infertility, and long-term complications like diabetes, cardiovascular problems, etc.

Aim

Study was aimed at finding the prevalence, characteristics, and various risk factors of metabolic syndrome (MS) in reproductive age group in our hospital.

Materials and methods

Using statistical table, a sample size of 131 was calculated and patients were recruited as per inclusion criteria. Polycystic ovarian syndrome was diagnosed by the American Society for Reproductive Medicine (ASRM)/European Society of Human Reproduction and Embryology (ESHRE) criteria. After informed consent, a detailed history was obtained and physical examination was carried out to assess, body weight, height, body mass index (BMI), waist—hip ratio (WHR), and blood pressure (BP). Fasting blood glucose, triglycerides, and high-density lipoprotein (HDL) were measured for each woman

Results

Prevalence of MS in our study was 45.8%; 26.7% of patients had a combination of increased waist circumference, raised triglycerides, and low HDL; 55.2% of patients had a fasting blood sugar (FBS) levels more than 100 mg%. Age of the patient was a statistically significant risk factor of MS with 100% of patients in the age group of 35 to 39 presenting with MC. Body mass index was also a statistically significant risk factor with 82.6% with BMI > 30 having MC. Other important risk factors include a WHR more than 0.95, presence of diabetes in mother or sister, and presence of acanthosis; 71% of patients with WHR more than 0.95 had MC. Age of menarche, duration of menstrual cycles, and hirsutism showed no significant relationship.

Conclusion

An outstanding fact that emerged in this study was that 94% of women with PCOS had HDL values <50 mg/dL. And 58% had triglycerides more than 150 mg/dL. Hence, lifestyle modification and early intervention will hopefully spare long-term complication of PCOS.

How to cite this article

Madusudhanan RR, Nambisan B, Brahmanandan M, Radha S. Study on the Prevalence and Characteristics of Metabolic Syndrome in Women of Reproductive Age Group with Polycystic Ovarian Syndrome. J South Asian Feder Obst Gynae 2017;9(4):341-347.


HTML PDF Share
  1. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004;19(1):41-47.
  2. Prevalence of the polycystic ovary syndrome in unselected black and white woman of the south eastern United States: a prospective study. J Clin Endocrinol Metab 1998 Sep;83(9):3078-3082.
  3. A prospective study in the prevalence of the polycystic ovary syndrome in unselected Caucasian woman from Spain. J Clin Endocrinol Metab 2008 Jul;85(7):2434-2438.
  4. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev 1997 Dec;18(6):774-800.
  5. Trends in Coronary Heart Disease Epidemiology in India. Annals of global health. 2016 Mar-Apr;82(2):307-315.
  6. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988 Dec;37(12):1595-1607.
  7. The androgenic sex hormone profile is an essential feature of metabolic syndrome in premenopausal women: a controlled community-based study. Fertil Steril 2003 Jun;79(6):1327-1334.
  8. Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2005 Apr;90(4):1929-1935.
  9. Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome. Metabolism 2003 Jul;52(7):908-915.
  10. screening women with polycystic ovary syndrome for metabolic syndrome. Obstet Gynecol 2005 Jul;106(1):131-137.
  11. Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2006 Jan;91(1):48-53.
  12. Abdominal adiposity and coronary heart disease in women. JAMA 1998 Dec;280(21):1843-1848.
  13. Metabolic syndrome in urban Asian Indian adults – A population study using modified ATP III criteria. Diabetes Res Clin Pract. 2003;60:199–204
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.