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VOLUME 9 , ISSUE 3 ( July-September, 2017 ) > List of Articles

ORIGINAL ARTICLE

Neonatal Outcome and Its Correlation with Hemoglobin A1c in Gestational Diabetes Mellitus

Preksha Jain, Pritesh Jain

Citation Information : Jain P, Jain P. Neonatal Outcome and Its Correlation with Hemoglobin A1c in Gestational Diabetes Mellitus. J South Asian Feder Obs Gynae 2017; 9 (3):216-220.

DOI: 10.5005/jp-journals-10006-1498

License: CC BY 3.0

Published Online: 01-12-2012

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

Aim

To determine neonatal outcome in women with gestational diabetes mellitus (GDM) diagnosed using Diabetes in Pregnancy Study Group of India (DIPSI) recommended method.

Materials and methods

Out of 487 antenatal women, 52 were diagnosed with GDM using DIPSI test. All women were followed up until delivery and evaluated for neonatal outcome and managed accordingly. The appropriate statistical tests for various variables were applied by using Epi Info 7 software and evaluated at the level below than 5%.

Results

Apgar score of <6 at 5 minutes was found in 10 (20%) neonates of GDM mothers as compared with 18 (4.1%) in non-GDM group (p-value of 0.00001). Respiratory distress was present in 19 (38%) neonates in GDM group, while it was 48 (11.1%) in non-GDM group (p-value of 0.00002). Association of GDM and hyperbilirubinemia was nonsignificant in 2 (4%) neonates among GDM group, while it was 6 (1.4%) in non-GDM group. Hypoglycemia was 5 (10%) in GDM group, while 3 (0.7%) in non-GDM group (p-value of <0.0003). A total of 3 (6%) among GDM group had hypocalcemia, while 3 (0.7%) had hypocalcemia in non-GDM group (p-value of 0.02). The neonatal intensive care unit admissions were 29 (58%) in GDM group, while it was 96 (22.1%) neonates belonging to non-GDM group (p-value of 0.00001). No neonatal deaths were reported in GDM group, while there were 2 (0.5%) in non-GDM group. Anomalies were found in 6 (11.5%) in GDM group as compared with 5 (1.1%) in non-GDM (p-value of 0.00001). About 44.2% women with GDM had hemoglobin (Hb)A1c levels between 6 and 6.9%. Among GDM women, 4 (7.7%) had pregnancy losses as compared with 7 (1.6%) in non-GDM group.

Conclusion

The GDM is associated with significant fetal and neonatal morbidity; hence, preconceptional counseling, early diagnosis, and proper treatment are recommended.

Clinical significance

Preconceptional correction of HbA1c is also recommended based on risk of anomalies in fetus of GDM mother.

How to cite this article

Jain P, Somalwar S, Jain P. Neonatal Outcome and Its Correlation with Hemoglobin A1c in Gestational Diabetes Mellitus. J South Asian Feder Obst Gynae 2017;9(3):216-220.

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