Unveiling Rarity: A Case Report on Clear Cell Carcinoma of Cervix
Madhuri Singh, Mangesh M Londhe, Akshi Raj, Sushama Gurwale, Charusheela Gore
Keywords :
Adenocarcinoma cervix, Cancer cervix, Case report, Clear cell carcinoma
Citation Information :
Singh M, Londhe MM, Raj A, Gurwale S, Gore C. Unveiling Rarity: A Case Report on Clear Cell Carcinoma of Cervix. J South Asian Feder Obs Gynae 2025; 17 (1):95-97.
Clear cell carcinoma (CCC) of cervix is an extremely rare malignancy, accounting to only 4% of all adenocarcinoma of cervix. The majority of cases are related to in utero diethylstilbestrol (DES) exposure and it rarely occurs sporadic. The diagnosis of CCC of the uterine cervix is mainly established based on histopathological examination. Clear cell carcinomas of cervix have a greater tendency to recur and develop metastases in distant sites; hence, even after treatment long-term follow-up is necessary to detect local and distant relapse. We report one such rare case of CCC of cervix in a 62-year-old postmenopausal woman with history of per vaginal (PV) spotting and with no history of DES exposure.
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