Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 16 , ISSUE S3 ( December, 2024 ) > List of Articles

RESEARCH ARTICLE

Outcome of Uterine Carcinosarcoma: A 5-year Institutional Review

Agniv Sarkar, Manoranjan Mahapatra, Jita Parija

Keywords : Carcinosarcoma, Endometrial carcinoma, Uterine cancer, Uterine carcinosarcoma, Uterine sarcoma

Citation Information :

DOI: 10.5005/jp-journals-10006-2572

License: CC BY-NC 4.0

Published Online: 03-02-2025

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Introduction: Uterine carcinosarcoma (CS) is an uncommon uterine malignancy that consists of 3–7% of all uterine malignancies. Survival is 40–70% in early stages. The objective is to estimate the incidence of carcinosarcoma in our institute and to analyze the demographic characteristics, intra-, and post-op features along with survival analysis. Methods and materials: It is a retrospective analysis of 5 years of data from 2016 to 2021. All the carcinosarcoma cases operated in our institute and operated elsewhere but received post-op adjuvant in our institute were included. Results and discussion: A total of 20 cases of uterine CS were managed in these 5 years which puts the incidence at 8.1% among all uterine malignancies. The median age was 54.8 years with most of the patients presenting with postmenopausal bleeding. Omental and ovarian involvement was seen in 10 and 15% of cases, respectively. Three-year PFS was 78% in stage IB and drops down to 25% in stage III. Conclusion: Uterine carcinosarcoma is a disease of predominantly post-menopausal age-group. Survival is better in early-stage disease implicating early diagnosis and management. Median OS value could not be achieved within the period.


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