Aim and background: Thrombocytopenia is defined as a decrease in the number of platelets. It is one of the, if not the most, common coagulation disorders that can complicate obstetrics. A normal count is arbitrarily set as 1,50,000–4,50,000 platelets per microliter. Case description: Thrombocytopenia unique to pregnancy can be gestational thrombocytopenia, preeclampsia-induced thrombocytopenia, HELLP syndrome, and acute fatty liver of pregnancy (AFLP). While the remaining causes that coincide with pregnancy include disseminated intravascular coagulation (DIC), immune thrombocytopenic purpura (ITP), hematological malignancies, pseudothrombocytopenia, Wilson's disease, and autoimmune disorders. The former necessitate urgent delivery to optimize maternal and fetal outcome, following which there is spontaneous resolution of thrombocytopenia. While in the latter, pregnancy doesn't compound the issue and is a mere coincidence and hence the inciting factor needs to be eradicated to resolve the thrombocytopenia and often even requires use of blood products. Conclusion: We attempt to discuss few cases of thrombocytopenia, seen at a tertiary care center and its multidisciplinary approach toward management. Clinical significance: The unique problem with thrombocytopenia in obstetrics is the diagnostic hurdle it can pose to determine whether the pregnancy is a latter event to pre-existing thrombocytopenia, or if pregnancy is the causative factor for the same. This, in turn, can significantly alter the mode and time of termination and hence the neonatal outcome.