Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 16 , ISSUE 4 ( July-August, 2024 ) > List of Articles

Original Article

A Comparative Study between Efficacy of Ferric Carboxymaltose and Iron Sucrose Complex for Treatment of Iron Deficiency Anemia in Pregnancy

Shravi Singh, Rajni Agarwal, Shehla Jamal, Mridula Sharma, Natasha Singh, Akansha Tyagi

Keywords : Anemia, Ferric carboxymaltose, Iron sucrose, Pregnancy

Citation Information : Singh S, Agarwal R, Jamal S, Sharma M, Singh N, Tyagi A. A Comparative Study between Efficacy of Ferric Carboxymaltose and Iron Sucrose Complex for Treatment of Iron Deficiency Anemia in Pregnancy. J South Asian Feder Obs Gynae 2024; 16 (4):369-372.

DOI: 10.5005/jp-journals-10006-2448

License: CC BY-NC 4.0

Published Online: 09-07-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Background: Intravenous iron administration is routinely used to treat moderate anemia during pregnancy. Iron sucrose has the disadvantage of repeated doses and increased hospital visits. Ferric carboxymaltose provides rapid replacement of iron storage in a single dose. In this study, we compare the safety and efficacy of the two parenteral iron complexes in the treatment of iron deficiency anemia in pregnancy from gestation age of 14–38 weeks. Methodology: The Obstetrics and Gynecology Department at Rajshree Medical Research Institute in Bareilly conducted this comparative investigation. In order to conduct the study, a total of 100 pregnant women who were diagnosed with moderate anemia between the ages of 14 and 36 weeks of gestation were divided into two groups at random (n = 50) (Group A: Iron sucrose complex (ISC); Group B: Ferric carboxymaltose). Result: In group A of the study, the majority of the patients were women between the ages of 26 and 30 (38%) and between 31 and 35 (44%), respectively. In group A, 8% of patients and 6% in group B had nausea. In group A, 1% of patients reported abdominal pain, whereas in group B, there were no complaints. Conclusion: There aren't many randomized controlled trials comparing ferrous carboxymaltose and ISC in pregnant women between 14 and 28 weeks along with very few prospective studies on FCM. The present study concludes Ferric carboxymaltose to be more efficient with no life-threatening reaction compared with ISC for treatment of moderate iron deficiency anemia in 14–36 weeks of gestation.


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