Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 16 , ISSUE 3 ( May-June, 2024 ) > List of Articles

CASE REPORT

A Case of Leiomyosarcoma of Vaginal Vault in a Post-hysterectomy Patient

Agniv Sarkar, Manoranjan Mahapatra, Jita Parija, Smruthisudha Pattnaik

Keywords : Case report, Leiomyosarcoma, Pelvic mass, Smooth muscle antigen-positive leiomyosarcoma, Spindle cell carcinoma

Citation Information : Sarkar A, Mahapatra M, Parija J, Pattnaik S. A Case of Leiomyosarcoma of Vaginal Vault in a Post-hysterectomy Patient. J South Asian Feder Obs Gynae 2024; 16 (3):313-314.

DOI: 10.5005/jp-journals-10006-2032

License: CC BY-NC 4.0

Published Online: 29-04-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Leiomyosarcoma usually arises de novo from uterine smooth muscle, although it may rarely arise from a preexisting leiomyoma. They are usually accompanied by pain, sensation of pressure, and abnormal uterine bleeding (AUB). Rapid enlargement of fibroid or rapidly increasing pain may be a symptom too. In this case, a 62-year-old woman came to the outpatient department (OPD) with a complaint of pain abdomen for the last 3 months. She is (P2L2), post-menopausal for the last 12 years. She had a history of total abdominal hysterectomy (TAH) + bilateral salpingo-oophorectomy (BSO) 10 years back. On examination, she had a pelvic mass of 8 × 6 cm solid variegated. Outside, fine needle aspiration cytology (FNAC) report revealed it to be a spindle cell carcinoma. In our institute, tumor markers came out to be normal and contrast-enhanced computed tomography (CECT) imaging suggested a solid mass arising from vaginal vault. On laparotomy, a solid mass of 8 × 8 cm was found attached to the vaginal vault. All other organs were normal. Final holoprosencephaly (HPE) report came out to be leiomyosarcoma with immunohistochemistry (IHC) of smooth muscle antigen (SMA)-positive.


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