Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 16 , ISSUE 3 ( May-June, 2024 ) > List of Articles

Original Article

Prevalence of Impaired Glucose Tolerance in Nonpregnant Polycystic Ovarian Syndrome Patients in a Hospital

Padmahasta Pilla, Shobha N Gudi

Keywords : Diabetes mellitus, Glucose intolerance, Obesity, Prevention of gestational diabetes mellitus and diabetes mellitus, Polycystic ovarian syndrome

Citation Information : Pilla P, Gudi SN. Prevalence of Impaired Glucose Tolerance in Nonpregnant Polycystic Ovarian Syndrome Patients in a Hospital. J South Asian Feder Obs Gynae 2024; 16 (3):203-208.

DOI: 10.5005/jp-journals-10006-2409

License: CC BY-NC 4.0

Published Online: 29-04-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Aim: To determine the prevalence of impaired glucose intolerance in nonpregnant women with polycystic ovarian syndrome (PCOS) attending the outpatient department of St. Philomena's Hospital in Bengaluru, Karnataka, India. To observe the effect of body mass index (BMI), family history of diabetes mellitus (DM), age, parity, and other contributing factors on glucose tolerance state among individuals with PCOS. Materials and methods: This observational study included an oral glucose tolerance test (OGTT) of 200 nonpregnant PCOS women aged (15–35 years) over a period of 2 years from December 2013 to November 2015 in the Department of Obstetrics and Gynaecology, St. Philomena's Hospital in Bengaluru, Karnataka, India. Based on the results, they were classified into three groups, normal glucose tolerance (NGT), impaired glucose tolerance (IGT), or newly diagnosed DM. Results: Among the 200 women with PCOS, 64 women had IGT and 14 were newly diagnosed diabetics. Most of them were in the age group of 26-30 years. Conclusion: Impaired glucose tolerance is found in 32% of the study population. Type 2 DM is found in 7% of the study population. Clinical significance: There is an increased incidence of glucose intolerance in PCOS women. Awareness about this will help to bring in regulated screening programs for diabetes in this population with emphasis on exercise and stricter modification of diet. It will also help in providing preconception counseling to avert immediate and long-term maternal and fetal complications of gestational diabetes mellitus (GDM), and preventing and postponing the early onset of DM and other features of the metabolic syndrome.


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