Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 15 , ISSUE 1 ( January-February, 2023 ) > List of Articles

Original Article

Fetomaternal Outcomes among Patients with Sickle Cell Disease: A Retrospective Study

Hiral Ashok Chaudhary, Dipa Pitre

Keywords : Heterozygous, Homozygous, Pulmonary hypertension, Vaso-occlusion

Citation Information : Chaudhary HA, Pitre D. Fetomaternal Outcomes among Patients with Sickle Cell Disease: A Retrospective Study. J South Asian Feder Obs Gynae 2023; 15 (1):34-38.

DOI: 10.5005/jp-journals-10006-2187

License: CC BY-NC 4.0

Published Online: 19-04-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Introduction: We are presenting a study on pregnancy with sickle cell disease (SCD), which is the most common genetic disorder with high mortality and morbidity with varying severity. It is an increasing global health problem. Materials and methods: The cases were retrieved and a case–control study was done at GMERS Medical College and Hospital over a duration of 3 years from November 2019 to September 2022. General characteristics of 32 pregnancies and their fetomaternal complications were studied. A descriptive statistical analysis of the above-mentioned data was performed, and percentages were calculated. Results: Among 32 cases, 62.5% of cases were multigravida. Anemia (moderate and severe anemia) was the most common complication (71.87%). Hemolytic crisis was seen in 18.75%, and painful crises were seen in 6.25% cases, 9.37% of cases had acute chest syndrome. Complications such as urinary tract infection (UTI) were seen in 6.25%, preeclampsia in 34.37%, 56.25% had preterm deliveries, and history of miscarriage and stillbirth was seen in 34.37%. Intrauterine growth restriction (IUGR) was seen in 9.37%, neonatal death – 3.12%, low birth weight – 62.5%, fetal distress – 12.50%, and intrauterine fetal death (IUFD) – 6.25%. Maternal mortality was seen in 12.50% cases. Discussion: Because of physiological adaptations along with sickle cell crisis, maternal and fetal complications are more in SCD patients. Conclusion: The study will help understand the outcomes of pregnancy in SCD patients and will help for a better approach in treating these patients.


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