Journal of South Asian Federation of Obstetrics and Gynaecology

Register      Login

VOLUME 15 , ISSUE 1 ( January-February, 2023 ) > List of Articles

Original Article

COVID-19 Vaccine: Knowledge and Acceptance among Obstetric Population in Garhwal Region of Uttarakhand

Purnima Upreti, Punam Godara

Keywords : COVID-19, Pregnant women, Vaccine acceptance, Vaccine hesitancy

Citation Information : Upreti P, Godara P. COVID-19 Vaccine: Knowledge and Acceptance among Obstetric Population in Garhwal Region of Uttarakhand. J South Asian Feder Obs Gynae 2023; 15 (1):5-11.

DOI: 10.5005/jp-journals-10006-2174

License: CC BY-NC 4.0

Published Online: 19-04-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Background: Coronavirus disease-2019 (COVID-19) poses expectant mothers to a higher risk of serious complications and mortality. Following a risk–benefit review, a number of governmental and professional bodies from across the globe recently approved the COVID-19 vaccination during pregnancy. Aim: This study aimed to investigate knowledge, actual acceptance, and concerns about the COVID-19 vaccine among the obstetric population. Materials and methods: Participants were selected from among the expecting women who came for antenatal checkup during the study period (October 1, 2021–November 30, 2021). About 150 pregnant women who met the inclusion criteria and consented were recruited into the study. Data related to socio-demographic and clinical characteristics as well as knowledge, actual acceptance, and concerns about COVID-19 vaccine were collected through in-person interviews using a prestructured questionnaire. The SPSS version 23 was used to analyze data. The association between the attitude (acceptance and hesitance) of participants toward the COVID-19 vaccine and their sociodemographic and clinical profile was found by Fisher's exact test. Results: The actual acceptance of the COVID-19 vaccine among expecting women was 52.0%. The primary motive for accepting COVID-19 immunization was to protect the fetus, followed by the protection of one's own health. A significant association was found between COVID-19 vaccine acceptance and the level of education, socio-economic status, and presence of comorbidities. The leading causes for vaccine reluctance were concerns about the efficacy and safety of the vaccines and lack of awareness about their usage during pregnancy. Conclusion: Multifaceted activities are required to promote the effectiveness and safety profile of the COVID-19 vaccine as well as disseminate knowledge about its usage during pregnancy. Clinical significance: Unlike numerous other studies that have investigated the accepting attitude only, the present one has investigated the actual COVID-19 vaccine uptake among the obstetric population.


PDF Share
  1. Rasmussen SA, Smulian JC, Lednicky JA, et al. Coronavirus disease 2019 (COVID-19) and pregnancy: What obstetricians need to know. Am J Obstet Gynecol 2020;222(5):415–426. DOI: 10.1016/j.ajog. 2020.02.017.
  2. López M, Gonce A, Meler E, et al. Coronavirus disease 2019 in pregnancy: A clinical management protocol and considerations for practice. Fetal Diagn Ther 2020;47(7):519–528. DOI: 10.1159/000508487.
  3. Allotey J, Stallings E, Bonet M, et al. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: Living systematic review and meta-analysis. BMJ 2020; 370. DOI: 10.1136/bmj.m3320.
  4. Collin J, Byström E, Carnahan AS, et al. Public Health Agency of Sweden's Brief Report: Pregnant and postpartum women with severe acute respiratory syndrome coronavirus 2 infection in intensive care in Sweden. Acta Obstet Gynecol Scand 2020;99(7):819–822. DOI: 10.1111/aogs.13901.
  5. Martins I, Louwen F, Ayres-de-Campos D, et al. EBCOG position statement on COVID-19 vaccination for pregnant and breastfeeding women. Eur J Obstet Gynecol Reprod Biol 2021;262:256–258. DOI: 10.1016/j.ejogrb.2021.05.021.
  6. Abu-Raya B. Vaccination of pregnant women against COVID-19. Neoreviews 2021;22(9):e570–e573. Available from: https://pubmed.ncbi.nlm.nih.gov/34470758/.
  7. Joint Committee on Vaccination and Immunisation: Advice on priority groups for COVID-19 vaccination, 30 December 2020 - GOV.UK. Available from: https://www.gov.uk/government/publications/priority-groups-for-coronavirus-covid-19-vaccination- advice-from-the-jcvi-30-december-2020/joint-committee-on-vaccination-and-immunisation-advice-on-priority-groups-for-covid-19-vaccination-30-december-2020.
  8. COVID-19 Vaccines, Pregnancy and Breastfeeding FAQs | RCOG [cited 2022 Aug 8]. Available from: https://www.rcog.org.uk/guidance/coronavirus-covid-19-pregnancy-and-women-s-health/vaccination/covid-19-vaccines-pregnancy-and-breastfeeding-faqs/.
  9. Stafford IA, Parchem JG, Sibai BM. The coronavirus disease 2019 vaccine in pregnancy: Risks, benefits, and recommendations. Am J Obstet Gynecol 2021;224(5):484–495. DOI: 10.1016/j.ajog.2021. 01.022.
  10. Chervenak FA, McCullough LB, Bornstein E, et al. Professionally responsible coronavirus disease 2019 vaccination counseling of obstetrical and gynecologic patients. Am J Obstet Gynecol 2021;224(5):470–478. DOI: 10.1016/j.ajog.2021.01.027.
  11. The Moderna COVID-19 (mRNA-1273) Vaccine: What you Need to Know. [cited 2022 Aug 8]. Available from: https://www.who.int/news-room/feature-stories/detail/the-moderna-covid-19-mrna-1273-vaccine-what-you-need-to-know.
  12. COVID-19 Vaccines While Pregnant or Breastfeeding. [cited 2022 Aug 8]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/pregnancy.html.
  13. Operational Guidance for COVID-19 Vaccination of Pregnant Women Background. [cited 2022 Aug 8]. Available from: https://www. mohfw.gov.in/pdf/GuidancedocCOWIN2.pdf.
  14. 6th National Technical Advisory Group on Immunization (NTAGI) Meeting (Through Video Conferencing).
  15. Shimabukuro TT, Kim SY, Myers TR, et al. Preliminary findings of mRNA COVID-19 vaccine safety in pregnant persons. N Engl J Med 2021;384(24):2273–2282. DOI: 10.1056/NEJMoa2104983.
  16. Goncu Ayhan S, Oluklu D, Atalay A, et al. COVID-19 vaccine acceptance in pregnant women. Int J Gynaecol Obstet 2021;154(2):291–296. DOI: 10.1002/ijgo.13713.
  17. Skjefte M, Ngirbabul M, Akeju O, et al. COVID-19 vaccine acceptance among pregnant women and mothers of young children: Results of a survey in 16 countries. Eur J Epidemiol 2021;36(2):197–211. DOI: 10.1007/s10654-021-00728-6.
  18. Mose A, Yeshaneh A. COVID-19 vaccine acceptance and its associated factors among pregnant women attending antenatal care clinic in Southwest Ethiopia: Institutional-based cross-sectional study. Int J Gen Med 2021;14:2385–2395. DOI: 10.2147/IJGM.S314346.
  19. Sutton D, D'Alton M, Zhang Y, et al. COVID-19 vaccine acceptance among pregnant, breastfeeding, and nonpregnant reproductive-aged women. Am J Obstet Gynecol MFM 2021;3(5):100403. DOI: 10.1016/j.ajogmf.2021.100403.
  20. Tao L, Wang R, Han N, et al. Acceptance of a COVID-19 vaccine and associated factors among pregnant women in China: A multi-center cross-sectional study based on health belief model. Hum Vaccin Immunother 2021;17(8):2378–2388. DOI: 10.1080/21645515. 2021.1892432.
  21. Nguyen LH, Hoang MT, Nguyen LD, et al. Acceptance and willingness to pay for COVID-19 vaccines among pregnant women in Vietnam. Trop Med Int Health 2021;26(10):1303–1313. DOI: 10.1111/tmi. 13666.
  22. Pairat K, Phaloprakarn C. Acceptance of COVID-19 vaccination during pregnancy among Thai pregnant women and their spouses: A prospective survey. Reprod Health 2022;19(1):74. DOI: 10.1186/s12978-022-01383-0.
  23. Kasemy ZA, Bahbah WA, Zewain SK, et al. Knowledge, attitude and practice toward COVID-19 among Egyptians. J Epidemiol Glob Health 2020;10(4):378–385. DOI: 10.2991/jegh.k.200909.001.
  24. Mohan S, Reagu S, Lindow S, et al. COVID-19 vaccine hesitancy in perinatal women: A cross-sectional survey. J Perinat Med 2021;49(6):678–685. DOI: 10.1515/jpm-2021-0069.
  25. Mappa I, Luviso M, Distefano FA, et al. Women perception of SARS-CoV-2 vaccination during pregnancy and subsequent maternal anxiety: A prospective observational study. J Matern Fetal Neonatal Med 2021:1–4. Available from: https://doi.org/10.1080/14767058. 2021.1910672.
  26. Stuckelberger S, Favre G, Ceulemans M, et al. SARS-CoV-2 vaccine willingness among pregnant and breastfeeding women during the first pandemic wave: A cross-sectional study in Switzerland. Viruses 2021;13(7):1199. DOI: 10.3390/v13071199.
  27. Geoghegan S, Stephens LC, Feemster KA, et al. “This choice does not just affect me.” Attitudes of pregnant women toward COVID-19 vaccines: A mixed-methods study. Hum Vaccin Immunother 2021;17(10):3371–3376. DOI: 10.1080/21645515.2021.1924018.
  28. 10 global health issues to track in 2021. [cited 2022 Aug 8]. Available from: https://www.who.int/news-room/spotlight/10-global-health-issues-to-track-in-2021.
  29. Gray KJ, Bordt EA, Atyeo C, et al. Coronavirus disease 2019 vaccine response in pregnant and lactating women: A cohort study. Am J Obstet Gynecol 2021;225(3):303.e1–303.e17. DOI: 10.1016/j.ajog.2021. 03.023.
  30. Syed Alwi SAR, Rafidah E, Zurraini A, et al. A survey on COVID-19 vaccine acceptance and concern among Malaysians. BMC Public Health 2021;21(1):1129. Available from: https://doi.org/10.1186/s12889-021-11071-6.
  31. Neumann-Böhme S, Varghese NE, Sabat I, et al. Once we have it, will we use it? A European survey on willingness to be vaccinated against COVID-19. Eur J Health Econ 2020;21(7):977–982. DOI: 10.1007/s10198-020-01208-6.
  32. Harapan H, Wagner AL, Yufika A, et al. Acceptance of a COVID-19 vaccine in Southeast Asia: A cross-sectional study in Indonesia. Front Public Health 2020;8:381. DOI: 10.3389/fpubh.2020.00381.
  33. Dereje N, Tesfaye A, Tamene B, et al. COVID-19 vaccine hesitancy in Addis Ababa, Ethiopia: A mixed-method study. BMJ Open 2022;12(5):e052432. DOI: 10.1136/bmjopen-2021-052432.
  34. Hoque AM, Buckus S, Hoque M, et al. COVID-19 vaccine acceptability among pregnant women at a Primary Health Care Facility in Durban, South Africa. Eur J Med Heal Sci 2020;2(5). Available from: https://doi.org/10.24018/ejmed.2020.2.5.493.
  35. Lazarus JV, Ratzan SC, Palayew A, et al. A global survey of potential acceptance of a COVID-19 vaccine. Nat Med 2021;27(2):225–228. DOI: 10.1038/s41591-020-1124-9.
  36. Garg R, Lal P, Agrawal P, et al. Menstrual cycle changes after COVID-19 infection: Does coronavirus-induced stress lead to hormonal change? J South Asian Feder Obst Gynae 2022;14(3):248–252. Available from: https://doi.org/10.5005/jp-journals-10006-2027.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.