Aim: To diagnose a rare congenital liver disorder, Dubin–Johnson Syndrome (DJS), compounded by pregnancy and its several differential diagnoses that impede the progress toward diagnosis. Background: Icterus, or jaundice, is defined as the yellow discoloration of the skin, more so of the sclera. While it classifies as one of the most common symptoms in medical literature, it gains added significance when it arrives in congruence to pregnancy. And with that added significance comes the increased risk of maternal and fetal morbidities and mortalities. Case description: Here, we discuss a 19-year-old antenatal patient with refractory hyperbilirubinemia whose etiology eluded our team, until a final shot at it through liver biopsy helped us fetch a surprising diagnosis of DJS. Conclusion: A nonfatal clinical syndrome with very few comorbidities, pregnancy at worst, worsens the icteric component without producing too many adverse fetomaternal outcomes. Clinical significance: The aid of a sound algorithm to rule out other more morbid causes of hepatic dysfunction in pregnancy.