Comparative Study of Maternal Mortality in SARS-CoV-2 Infected Pregnant Women in the First and Second Waves of COVID-19 Pandemic in Tertiary Care at Madhya Pradesh, India

Sunita Mishra; Neeta Natu; Nootan Chandwaskar; Bhanu Pratap Singh Dhakar; Susmit Kosta

doi:10.5005/jp-journals-10006-2106

SEARCH WITHIN CONTENT

Online First

Comparative Study of Maternal Mortality in SARS-CoV-2 Infected Pregnant Women in the First and Second Waves of COVID-19 Pandemic in Tertiary Care at Madhya Pradesh, India

Sunita Mishra, Neeta Natu, Nootan Chandwaskar, Bhanu Pratap Singh Dhakar, Susmit Kosta

Keywords : COVID-19, Maternal mortality, Pandemic, Pregnant women, Severe acute respiratory syndrome coronavirus 2

Citation Information : Mishra S, Natu N, Chandwaskar N, Dhakar BP, Kosta S. Comparative Study of Maternal Mortality in SARS-CoV-2 Infected Pregnant Women in the First and Second Waves of COVID-19 Pandemic in Tertiary Care at Madhya Pradesh, India. J South Asian Feder Obs Gynae 2022; 14 (4):400-403.

DOI: 10.5005/jp-journals-10006-2106

License: CC BY-NC 4.0

Published Online: 22-08-2022

ARTICLE
REFERENCES

Abstract

Objectives: To evaluate the obstetrics outcome in terms of maternal mortality in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected pregnant women in both the waves of coronavirus disease 2019 (COVID-19) pandemic. Design, settings, and participants: This is a prospective cohort study of obstetrics outcomes in SARS-CoV-2 infected pregnant women in both the waves of COVID-19 pandemic from 1 April 2020 to 30 May 2021 at Sri Aurobindo Institute of Medical Sciences with wide spread access to SARS-CoV-2 testing in outpatients, emergency department, and inpatient settings. Result: The primary outcome composed of maternal mortality in SARS-CoV-2 infected females during both waves of COVID-19 pandemic. Study shows that the second wave was more intense and fatal as compared to the first wave of COVID-19 pandemic in India with higher maternal mortality rate in the second wave than the first wave. Study also showed that an overall higher mortality with cesarean section was noted. Thus, our study concluded that the cesarean section is not the preferred mode of delivery in COVID-19 females suffering from respiratory distress. Conclusion: Our study concluded that cesarean section is not the preferred mode of delivery in COVID-19 with females suffering from respiratory distress. The SARS-CoV-2 infection during pregnancy was associated with adverse maternal outcomes post-delivery.

PDF Share

Vahidy FS, Drews AL, Masud FN, et al. Characteristics and outcomes of COVID-19 patients during initial peak and resurgence in the Houston metropolitan area. JAMA 2020;324(1):998–1000. DOI: 10.1001/jama.2020.15301.
Fan G, Yang Z, Lin Q, et al. Decreased case fatality rate of COVID-19 in the second wave: a study in 53 countries or regions. Transbound Emerg Dis 2020; 8(2):213–215. DOI: 10.1111/tbed.13819.
Saito S, Asai Y, Matsunaga N, et al. First and second COVID-19 waves in Japan: A comparison of disease severity and characteristics: a comparison of the two COVID-19 waves in Japan. J Infect 2020;82(4):84–123. DOI: 10.1016/j.jinf.2020.10.033.
Renardy M, Eisenberg M, Kirschner D. Predicting the second wave of COVID-19 in Washtenaw County, MI. J Theor Biol 2020;507:110461. DOI: 10.1016/j.jtbi.2020.110461.
Government of India, Ministry of Health and Family Welfare. COVID-19. Available at: https://www.mohfw.gov.in/ Accessed on: 19 May 2021.
Jain VK, Iyengar KP, Vaishya R. Differences between first wave and second wave of COVID-19 in India. Diabetes Metab Syndr 2021;15(3):1047–1048. DOI: 10.1016/j.dsx.2021.05.009.
Hippich M, Sifft P, Zapardiel–Gonzalo J, et al. A public health antibody screening indicates a marked increase of SARS-CoV-2 exposure rate in children during the second wave. Med (N Y). 2021;2(5):571–572. DOI: 10.1016/j.medj.2021.03.019.
Jalali SF, Ghassemzadeh M, Mouodi S, et al. Epidemiologic comparison of the first and second waves of coronavirus disease in Babol, North of Iran. Caspian J Intern Med 2020;11(Suppl 1):544–550. DOI: 10.22088/cjim.11.0.544.
Wong SF, Chow KM, Leung TN. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol 2004;191:292–297. DOI: 10.1016/j.ajog.2003.11.019.
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395(10223):497–506. DOI: 10.1016/S0140-6736(20)30183-5.
Agarwal N, Garg R, Singh S, et al. Coronavirus disease 2019 in pregnancy: maternal and perinatal outcome. J Educ Health Promot 2021;10(1):194. DOI: 10.4103/jehp.jehp_954_20.
Mascio DD, Khalil A, Saccone G. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM 2020;2(2):100107. DOI: 10.1016/j.ajogmf.2020.100107.
Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses 2020;12(2):194. DOI: 10.3390/v12020194.
Bisht R, Kandalgaonkar VP, Shinde KK. Cesarean section rate among COVID-19 mothers and its classification through Robson's criteria. JSAFOG 2021:355–359. DOI: 10.5005/jp-journals-10006- 1921.
Rashid F, Shahnaz S, Sharmin R, et al. Pregnancy with COVID-19: weal and woe. JSAFOG 2020;12(4):258–260. DOI: 10.5005/jp-journals-10006-1798.
Kadiwar S, Smith JJ, Ledot S, et al. Were pregnant women more affected by COVID-19 in the second wave of the pandemic? Lancet 2021;397(10284):1539–1540. DOI: 10.1016/S0140-6736(21)00716-9.
Iftimie S, López–Azcona AF, Vallverdú I, et al. First and second waves of coronavirus disease-19: a comparative study in hospitalized patients in Reus, Spain. PloS One. 2021;16(3):e0248029. DOI: 10.1371/journal.pone.0248029.

PDF Share