Aim: To understand a systematic and meticulous approach towards Wilson disease, a genetic disorder of copper metabolism, complicating pregnancy. Background: Wilson's disease results in increased body retention of copper and its eventual toxicity and related effects on several organ systems, especially neurological and hepatic. Case description: Here we study a case of a female with neuropsychiatric and hepatic manifestations of Wilson disease, conceiving spontaneously eventuating with a successful maternal and fetal outcome. Conclusion: With the accurate application of a multidisciplinary team approach with timely investigations, imaging studies, and counseling, successful maternal and fetal outcome in Wilson disease is well within our reach. Clinical significance: Women of reproductive age-groups with Wilson disease, face recurrent miscarriages and poor obstetric outcomes due to copper deposition in the body with the concomitant chronic liver disease and its sequelae making management challenging.