Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 14 , ISSUE 3 ( May-June, 2022 ) > List of Articles


Gynandroblastoma: A Rare Presentation

Arzoo Alagh, Samarth Shukla, Neema Acharya, Sunita Vagha

Keywords : Granulosa–theca cell, Gynandroblastoma, Sertoli–Leydig cell, Sex cord-stromal tumor

Citation Information : Alagh A, Shukla S, Acharya N, Vagha S. Gynandroblastoma: A Rare Presentation. J South Asian Feder Obs Gynae 2022; 14 (3):334-336.

DOI: 10.5005/jp-journals-10006-2064

License: CC BY-NC 4.0

Published Online: 30-07-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Gynandroblastoma is the sex cord-stromal tumor composed of clearly identifiable granulosa–theca cell and Sertoli–Leydig cell elements in variable amounts which comprise less than 1% of the sex cord-stromal tumors. Very few cases of gynandroblastoma are present in the literature to our knowledge. We discuss a case of gynandroblastoma of the ovary in a 62-year-old menopausal female. The microscopic features of the tumor showed both Sertoli cell and granulosa cell component. These tumors are associated with hormonal imbalance as the cells involved participate in the ovarian hormonal function. Thus, extensive sectioning of the tumor must be done by the surgical pathologist to rule out the possibility of other tumors and provide with a correct diagnosis of the tumor which can help the clinicians to plan an adequate management protocol for this rare tumor which will further elucidate into a properly regulated hormonal status and a better quality of life for the patients.

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