Introduction: Ectopic pregnancy (EP) is a pregnancy complication where the fertilized egg is implanted in an area other than the uterus. In 98% of EP cases, the implantation of the egg occurs within the fallopian tube. It can happen due to many factors related to the patient\'s history and sexual and reproductive history. This research is aimed to study the association between EP and Chlamydia trachomatis infection and also other risk factors.
Methodology: The study was conducted in the Department of Obstetrics and Gynecology, Chattogram Medical College Hospital, Bangladesh. Women with ruptured EP were selected as cases; women undergoing tubal ligation were taken as control. The biological test was conducted using PCR to detect the presence of the Chlamydia bacteria in the specimens collected from both the cases and controls. The collected data were analyzed using IBM SPSS version 20.0.
Results: The average age of the cases was 27.55 ± 5.32 years, and the average age of the control was 31.61 ± 6.89 years; the age difference was not statistically significant (p >0.1). Medical history of individuals with sexual–reproductive health issues, such as parity, PID, abdominal pain, and vaginal bleeding, showed a significant connection (p = 0.1) with EP. In women, infection with C. trachomatis was strongly linked to tubal EP (15 positive cases out of 22). The presence of C. trachomatis infection, parity, abdominal discomfort, vaginal bleeding, and PID results was significant at a 90% confidence interval (p <0.1) using binary logistic regression for all variables to predict which factors affect the dependent variable. Tubal EP is 5.7 times more common in women infected with C. trachomatis.
Conclusion: This study proved a strong association between the presence of C. trachomatis infection and EP. For future studies, using a greater sample size and investigating other microbes are suggested for better results.
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