Correlation between the Physical Signs, Clinical Parameters, and the Quality of Life in Young Women with Polycystic Ovarian Syndrome: An Explorative Study
Pramila D\'Souza, Devina E Rodrigues, Raja Gopal Kaipangala, Leena Kunnath Chacko, Joylene D Almeida
Acne, Body mass index, Lifestyle, Psychological health
Citation Information :
D\'Souza P, Rodrigues DE, Kaipangala RG, Chacko LK, Almeida JD. Correlation between the Physical Signs, Clinical Parameters, and the Quality of Life in Young Women with Polycystic Ovarian Syndrome: An Explorative Study. J South Asian Feder Obs Gynae 2022; 14 (1):17-21.
Aims and objectives: The study was aimed to investigate the relationship between the physical signs, clinical parameters, and the quality of life in young women with PCOS.
Materials and methods: A prospective cross-sectional survey was conducted among 140 women diagnosed with PCOS. The subjects who attended the outpatient department of obstetrics and gynecology were selected through the kth sampling technique. Baseline information was collected by an interview technique. The following parameters were then noted and assessed: BMI, waist/hip ratio, hirsutism, and acne. The standardized tool, WHOQOL-BREF scale, was used to find the quality of life.
Results: The majority of the subjects were between the age-group of 21–25 years (41.4%), and the mean age was 22.0 ± 0.74. Out of 140 PCOS women, 84 of them adopted the sedentary lifestyle category, 88 of women were residing in the urban area, and 106 subjects did not have a family history of PCOS. The total of 52.9% of the subjects were with amenorrhea, 55.8% of them were obese, 66.43% of subjects were with increased waist/hip ratio, 98.58% of the subjects had complaints of hirsutism, and 42.86% of subjects were with mild and moderate types of acne. The mean and SD of quality of life score in various domains were as follows: physical health, 20.07 ± 2.79; psychological health, 16.85 ± 3.06; social relationships, 18.17 ± 1.82; and environment, 40.00 ± 22.73. The overall perception of the quality of life is 22.73 ± 4.20, and the overall perception of satisfaction with health is 2.64 ± 0.89. There was no relationship between the PCOS symptoms and quality of life.
Conclusion: The research underlined the poor health-related quality of life. Acne is one of the leading factors that affected the health-related quality of life.
Clinical significance: The article is relevant in the present context where our current sedentary lifestyle and stressful living have induced changes among women, causing a sharp rise in the incidence of PCOD.
Royal College of Obstetricians and Gynaecologists. Long-term consequences of polycystic ovary syndrome. RCOG Green-top Guideline No. 33. 2014. p. 3–15.
Khan A, Karim N, Ainuddin J, et al. Polycystic ovarian syndrome: correlation between clinical hyperandrogenism, anthropometric, metabolic and endocrine parameters. Pak J Med Sci 2019;35(5): 1227–1232. DOI: 10.12669/pjms.35.5.742.
Abassum F, Jyoti C, Sinha HH, et al. Impact of polycystic ovary syndrome on quality of life of women in correlation to age, basal metabolic index, education and marriage. PLoS One 2021;16(3):e0247486. DOI: 10.1371/journal.pone.0247486.
Kumari M, Walavalkar R, Shaikh M, et al. Prevalence of polycystic ovary syndrome among women in Mumbai and association of its symptoms with work hours. IJOI Res Sci Eng Technol 2017;6(7). ISSN(Online): 2319-8753 ISSN (Print): 2347-6710. DOI: 10.15680/IJIRSET.2017.0607117.
Haq N, Khan Z, Riaz S, et al. Prevalence and knowledge of polycystic ovary syndrome (PCOS) among female science students of different public universities of Quetta, Pakistan. Imp J Interdiscip Res (IJIR) 2017;3(6):384–392. ISSN: 2. Available from: https://www.researchgate.net/publication/317400662.
Ferrer S, Adoamnei E, Prieto-Sánchez MT, et al. Health-related quality of life in women with polycystic ovary syndrome attending to a tertiary hospital in Southeastern Spain: a case-control study. Health Qual Life Outcomes 2020;18(1):232. DOI: 10.1186/s12955-020-01484-z.
Hahn S, Janssen O, Tan S, et al. Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. Eur J Endocrinol 2005;153:853–860. DOI: 10.1530/eje.1.02024.
Schroede MB. ACOG releases guidelines on diagnosis and management of polycystic ovary syndrome. Am Fam Physician 2003;67(7):1619–1622. PMID: 12722867.
Teede HJ, Misso ML, Costello MF, et al. International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod 2018;33(9):1602–1618. DOI: 10.1093/humrep/dey256. Erratum in: Hum Reprod. 2019;34(2):388. PMID: 30052961.
Chaudhari AP, Mazumdar K, Mehta PD. Anxiety, depression, and quality of life in women with polycystic ovarian syndrome. Indian J Psychol Med 2018;40(3):239–246. DOI: 10.4103/IJPSYM.IJPSYM_561_17.
Waist circumference and waist-hip ratio report of a WHO expert consultation, Geneva, 8–11 December 2008.
Ferriman D, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 1961;21(11),1440–1447. DOI: 10.1210/jcem-21-11-1440.
Thappa D, Adityan B, Kumari R. Scoring systems in acne vulgaris. Indian J Dermatol Venereol Leprol 2009;75(3):323–326. DOI: 10.4103/0378-6323.51258.
World Health Organization. WHO QOL User Manual. Programme on Mental Health. Available at: www.who.int/mental_health/media/en/620.pdf [last accessed on June, 2020].
Pathak G, Nichter M. Polycystic ovary syndrome in globalizing India: An ecosocial perspective on an emerging lifestyle disease. Soc Sci Med 2015;146:21–28. DOI: 10.1016/j.socscimed.2015.10.007. PMID: 26479193.
Balaji S, Amadi C, Prasad S, et al. Urban rural comparisons of polycystic ovary syndrome burden among adolescent girls in a hospital setting in India. BioMed Res Int 2015;1–10. Article ID 158951, 10 p. DOI: 10.1155/2015/158951.
Jones GL, Hall JM, Balen AH, et al. Health-related quality of life measurement in women with polycystic ovary syndrome: a systematic review. Hum Reprod Update 2008;14(1):15–25. DOI: 10.1093/humupd/dmm030.
Tcher B, Fessler S, Friedl F. Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G. Arch Gynecol Obstet 2018;297:1027–1035. DOI: 10.1007/s00404-017-4623-2.