Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 13 , ISSUE 3 ( May-June, 2021 ) > List of Articles

RESEARCH ARTICLE

Role of Mean Arterial Pressure in Mid-trimester Pregnancy for the Prediction of Gestational Hypertension and Pre-eclampsia

Ojasvi Shanker, Mamta Gupta

Keywords : Gestational hypertension, Mean arterial pressure, Prediction of pre-eclampsia, Pre-eclampsia

Citation Information : Shanker O, Gupta M. Role of Mean Arterial Pressure in Mid-trimester Pregnancy for the Prediction of Gestational Hypertension and Pre-eclampsia. J South Asian Feder Obs Gynae 2021; 13 (3):151-155.

DOI: 10.5005/jp-journals-10006-1898

License: CC BY-NC 4.0

Published Online: 09-09-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background: Reliable markers for the prediction of pre-eclampsia (PE) and reducing its associated maternal and perinatal morbidity are lacking. Aims and objectives: To evaluate the role of mean arterial pressure (MAP) in the second trimester of pregnancy for predicting gestational hypertension (GH) and PE. Materials and Methods: Three-hundred and sixteen healthy and normotensive women were enrolled in the second trimester of pregnancy. The mean MAP for the woman was recorded as an average of two MAPs at 3–4 week intervals during the second trimester of pregnancy. All women were followed till term/delivery to predict the development of GH and pre-eclampsia later. Results: The performance of MAP for predicting the GH and PE was found to be very good. The area under the receiver operating characteristic (AUROC) for GH was 0.892 with sensitivity and specificity of 84.2 and 84.9%, respectively, whereas the AUROC for PE was 0.948 with sensitivity and specificity of 83.3 and 84.9%, respectively. Conclusion: MAP in the second trimester of pregnancy can be used to triage women with low-risk pregnancy for pregnancy hypertension. Clinical significance: Mid-trimester MAP is a very good parameter for the prediction of GH and PE. It should be routinely used for risk triaging in low-risk women for the development of hypertension in pregnancy.


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