Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 13 , ISSUE 3 ( May-June, 2021 ) > List of Articles

RESEARCH ARTICLE

Ultrasonography and Doppler Study to Predict Uterine Receptivity in Infertile Patients Undergoing Embryo Transfer and its Correlation with Pregnancy Rate

Anshikha Arora, Jai K Goel, Ruchica Goel, Shashi B Arya, Neeraj Prajapati

Keywords : Assisted reproductive technique, In vitro fertilization, Pulsatality index

Citation Information : Arora A, Goel JK, Goel R, Arya SB, Prajapati N. Ultrasonography and Doppler Study to Predict Uterine Receptivity in Infertile Patients Undergoing Embryo Transfer and its Correlation with Pregnancy Rate. J South Asian Feder Obs Gynae 2021; 13 (3):146-150.

DOI: 10.5005/jp-journals-10006-1897

License: CC BY-NC 4.0

Published Online: 09-09-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: To study ultrasonographic and Doppler parameters to predict uterine receptivity in infertile patients undergoing embryo transfer (ET) and its correlation with pregnancy. Materials and methods: It was a prospective interventional study, conducted in the in vitro fertilization unit of the Department of Obstetrics and Gynecology at Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, on 60 patients who presented with infertility. Transvaginal ultrasound was done on the day of adding progesterone in the frozen ET cycle and the day of trigger in the stimulation cycle. To assess uterine receptivity, we analyzed the ultrasonographic and Doppler parameters. The original Applebaum uterine scoring system was used. This uterine scoring system included ultrasound parameters: endometrial thickness, endometrial layering, and myometrial echogenicity and Doppler parameters: endometrial blood flow, uterine artery pulsatility index (PI), myometrial contractions, and myometrial blood flow. Ovum pickup was done 36 hours after the trigger. Day 3 or day 5 good quality embryos were transferred. Serum beta-human chorionic gonadotropin was performed 14 days after ET to confirm the pregnancy. Results: Out of the 60 infertile patients who underwent ET, 38.3% conceived. Patients with a total score of 17–19 had a higher pregnancy rate of 62%. PI, myometrial contraction, and total Applebaum uterine score parameters were significantly (p <0.05) higher among patients with pregnancy than without pregnancy. Conclusion: Transvaginal sonography and color Doppler for predicting uterine receptivity by means of Applebaum uterine scoring system are simple, quick, effective, and reproducible methods. Clinical significance: Uterine scoring helps us in deciding whether ET should be performed in the present cycle or not.


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