Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 12 , ISSUE 5 ( September-October, 2020 ) > List of Articles


Homocysteinemia: A Rare Cause of Recurrent Pregnancy Loss Coexisting with Deep Vein Thrombosis

Neema Acharya

Citation Information : Acharya N. Homocysteinemia: A Rare Cause of Recurrent Pregnancy Loss Coexisting with Deep Vein Thrombosis. J South Asian Feder Obs Gynae 2020; 12 (5):328-330.

DOI: 10.5005/jp-journals-10006-1824

License: CC BY-NC 4.0

Published Online: 23-03-2021

Copyright Statement:  Copyright © 2020; The Author(s).


Deep vein thrombosis (DVT) and venous thromboembolism are major health problems and are leading causes of maternal morbidity and mortality. Recurrent pregnancy loss either early or late is a serious problem and has both psychological and physical impacts. Thrombophilia is one of the most important causes of DVT as well as recurrent pregnancy loss as it worsens the physiological hypercoagulable case which exists in pregnancy. Homocysteinemia is rare but an important cause of DVT and recurrent pregnancy loss. Serum homocysteine levels in pregnancy have been linked to preeclampsia, recurrent abortions, and low birth weight. Diagnosis of this condition is missed on a routine basis due to extremely less frequency of the evaluation of serum homocysteine levels. Here, we report a case of hyperhomocysteinemia as an underlying cause of bad obstetric history and DVT which are a few of the classic presentations of the entity seen in the single patient. The condition was diagnosed by a multidisciplinary approach.

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