Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 12 , ISSUE 5 ( September-October, 2020 ) > List of Articles


Pregnancy and Delivery in a Patient with CADASIL: A Case Report

Akhil M Velayudhan, Jyoti R Chandran, Sukumarapillai Jayasree, Rajeshwary Pillay, Vijay Kumar Bindu

Citation Information : Velayudhan AM, Chandran JR, Jayasree S, Pillay R, Bindu VK. Pregnancy and Delivery in a Patient with CADASIL: A Case Report. J South Asian Feder Obs Gynae 2020; 12 (5):326-327.

DOI: 10.5005/jp-journals-10006-1818

License: CC BY-NC 4.0

Published Online: 23-03-2021

Copyright Statement:  Copyright © 2020; The Author(s).


Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an autosomal dominant arteriopathy, caused by mutations in a gene called Notch3 on long arm of chromosome 19. It is very rare in pregnancy. This case report is presented to create awareness regarding investigating patients presenting with such illness for a better perinatal outcome.

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  2. Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis. Lancet 2001;358(9298):2049–2051. DOI: 10.1016/S0140-6736(01)07142-2.
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  5. Headache, primary headaches and their treatment. JAAFOG 2017;3(2):99–104.
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