Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 12 , ISSUE 3 ( May-June, 2020 ) > List of Articles

Original Article

Comparative Efficacy of Sublingual Misoprostol for Uterine Ripening 2, 6, and 12 Hours before Hysteroscopy in Postmenopausal Women

Parvaneh Sherafat, Mansoore Vahdat, Mansoore Gorginzade

Citation Information : Sherafat P, Vahdat M, Gorginzade M. Comparative Efficacy of Sublingual Misoprostol for Uterine Ripening 2, 6, and 12 Hours before Hysteroscopy in Postmenopausal Women. J South Asian Feder Obs Gynae 2020; 12 (3):142-144.

DOI: 10.5005/jp-journals-10006-1806

License: CC BY-NC 4.0

Published Online: 22-11-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Abstract

Introduction: Misoprostol is a therapeutic method for uterine ripening in postmenopausal women under hysteroscopy, and determination of best dosage and time of administration is important to attain the best outcomes. Objectives: This study was performed to determine and compare efficacy of sublingual misoprostol for uterine ripening 2, 6, and 12 hours before hysteroscopy in postmenopausal women. Materials and methods: In this randomized clinical trial, 103 postmenopausal women attending to Akbarabadi and Rasool Hospitals in 2017 and 2018 for hysteroscopy were enrolled and randomly assigned to receive sublingual misoprostol for uterine ripening either 2 or 6 hours or and 12 hours before hysteroscopy. The outcomes and adverse effects were determined and compared. Results: In this study, the frequency rate of complications and also the external and internal os diameters were alike across the three study groups (p value > 0.05). Conclusion: It may be concluded that efficacy of sublingual misoprostol for uterine ripening 2, 6, and 12 hours before hysteroscopy in postmenopausal women is same, and for this matter, use at 2 hours before hysteroscopy is recommended for further supervision and more convenience.


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