Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 11 , ISSUE 1 ( January-February, 2019 ) > List of Articles

CASE REPORT

False-positive Positron Emission Tracing/Computed Tomography Secondary to Suture Granuloma Formation in Early-stage Endometrial Cancer

Angelito Magno, Quenny MDA Alas, Chen-Ai Sung

Keywords : Endometrial cancer, False-positive PET/CT, Silk suture, Suture granuloma

Citation Information : Magno A, Alas QM, Sung C. False-positive Positron Emission Tracing/Computed Tomography Secondary to Suture Granuloma Formation in Early-stage Endometrial Cancer. J South Asian Feder Obs Gynae 2019; 11 (1):73-76.

DOI: 10.5005/jp-journals-10006-1654

License: CC BY-NC 4.0

Published Online: 01-02-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Suture granuloma formation can cause abnormal radiotracer uptake of 2-deoxy-2-[18F] fluoro-D glucose (FDG) in positron emission tracing/computed tomography (PET/CT) scan. It can be formed secondary to usage of silk suture during surgery as part of delayed host inflammatory reaction to a foreign body. Here, we report a case of a 61-year-old woman diagnosed with endometrial cancer who underwent tumor debulking surgery secondary to abnormal radiotracer uptake in PET/CT suspected as tumor recurrence which on histology revealed suture granuloma.


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  1. Kitajima K, Suenaga Y, Ueno Y, Maeda T, Ebina Y, Yamda H, et al. Preoperative risk stratification using metabolic parameters of (18)F-FDG PET/CT in patients with endometrial cancer. Eur J Nucl Med Mol Imaging 2015;42(8):1268-1275.
  2. Bollineni VR, Ytre-Hauge S, Bollineni-Balabay O, Salvesen HB, Haldorsen IS. High diagnostic value of 18F-FDG PET/CT in endometrial cancer: systematic review and meta-analysis of the literature. Journal of Nuclear Medicine. 2016 Jun 1;57(6):879-885.
  3. Lee SI, Catalano OA, Dehdashti F. Evaluation of gynecologic cancer with MR imaging, 18F-FDG PET/CT, and PET/MR imaging. J Nucl Med 2015;56(3):436-443.
  4. Tirumani SH, Shanbhogue AK, Prasad SR. Current concepts in the diagnosis and management of endometrial and cervical carcinomas. Radiol Clin North Am 2013;51(6)1087-1110.
  5. Chung HH, Kang KW, Cho JY, Kim JW, Park NH, Song YS, et al. Role of magnetic resonance imaging and positron emission tomography/computed tomography in preoperative lymph node detection of uterine cervical cancer. Am J Obstet Gynecol 2010;203(2):156.e1-e5.
  6. Fennel J, Scholber J, Grodsu AL, Volegova-Neher N, Henne K, Langer M, et al. MRI and FDG-PET/CT imaging in gynecological malignancies: the radiation oncology perspective. Q J Nucl Med Mol Imaging 2016;60(2):117-123.
  7. Signorelli M, Crivellaro C, Buda A, Guerra L, Fruscio R, Elisei F, et al. Staging of high-risk endometrial cancer with PET/ CT and sentinel lymph node mapping. Clin Nucl Med 2015;40(10):780-785.
  8. Nakajo M, Nakajo M, Nakayama H, Jinguji M, Nakabeppu Y, Higashi M, et al. Dexamethasone suppression FDG PET/CT for differentiating between true- and false-positive pulmonary and mediastinal lymph node metastasis in non-small cell lung cancer: a pilot study of FDG PET/CT after oral administration of dexamethasone. Radiology 2016;279(1):246-253.
  9. Rosenbaum SJ, Lind T, Antoch G, Bockisch A. False-positive FDG PET uptake – the role of PET/CT. Eur Radiol 2006;5:1054- 1065.
  10. Kikuchi M, Nakamoto Y, Shinohara S, Fujiwara K, Tona Y, Yamakazi H, et al. Suture granuloma showing false-positive finding on PET/CT after head and neck cancer surgery. Auris Nasus Larynx 2012;39(1):94-97.
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