VOLUME 10 , ISSUE 4S1 ( October-December, 2018 ) > List of Articles
Sandeep Mathur, Sunesh Kumar
Keywords : Conversion, Immature teratoma, Ovarian mature teratoma
Citation Information : Mathur S, Kumar S. Growing Teratoma Syndrome: An Enigma. J South Asian Feder Obs Gynae 2018; 10 (4S1):355-357.
DOI: 10.5005/jp-journals-10006-1623
License: CC BY-NC 4.0
Published Online: 01-01-2018
Copyright Statement: Copyright © 2018; The Author(s).
The phenomenon of growing teratoma syndrome (GTS) is a curious entity well recognized in testicular nonseminomatous germ cell tumors (NSGCT), but rare in ovarian immature teratomas. It involves the conversion of immature to mature components during or after chemotherapy with further growth in the size of the lesions but containing only mature elements on histopathology, which could be clinically confused with malignant recurrence. Treatment involves complete surgical excision. Prognosis is usually favorable if the disease if completely resected, however mortalities even though rare have been reported. We herein describe two rare cases, with clinical features, diagnosis, complications, and management of the condition.