Journal of South Asian Federation of Obstetrics and Gynaecology

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VOLUME 10 , ISSUE 4S1 ( October-December, 2018 ) > List of Articles


Growing Teratoma Syndrome: An Enigma

Sandeep Mathur, Sunesh Kumar

Keywords : Conversion, Immature teratoma, Ovarian mature teratoma

Citation Information : Mathur S, Kumar S. Growing Teratoma Syndrome: An Enigma. J South Asian Feder Obs Gynae 2018; 10 (4S1):355-357.

DOI: 10.5005/jp-journals-10006-1623

License: CC BY-NC 4.0

Published Online: 01-01-2018

Copyright Statement:  Copyright © 2018; The Author(s).


The phenomenon of growing teratoma syndrome (GTS) is a curious entity well recognized in testicular nonseminomatous germ cell tumors (NSGCT), but rare in ovarian immature teratomas. It involves the conversion of immature to mature components during or after chemotherapy with further growth in the size of the lesions but containing only mature elements on histopathology, which could be clinically confused with malignant recurrence. Treatment involves complete surgical excision. Prognosis is usually favorable if the disease if completely resected, however mortalities even though rare have been reported. We herein describe two rare cases, with clinical features, diagnosis, complications, and management of the condition.

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